DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgt1 and SGT1B

DIOPT Version :9

Sequence 1:	NP_649783.2	Gene:	Sgt1 / 40982	FlyBaseID:	FBgn0265101	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_192865.1	Gene:	SGT1B / 826728	AraportID:	AT4G11260	Length:	358	Species:	Arabidopsis thaliana

Alignment Length:	198	Identity:	77/198 - (38%)
Similarity:	112/198 - (56%)	Gaps:	25/198 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RHDWYQSETKVVITVLLKNAVDKNYAVEITQKRVHMTAD-----GYELDLKLLHPIVVERSSYKA 63
            ||::||...:.|:|:..|....:|..||..::.:.:..|     .|.|..:|...|:.|:..::.
plant   161 RHEFYQKPEEAVVTIFAKKVPKENVTVEFGEQILSVVIDVAGEEAYHLQPRLFGKIIPEKCRFEV 225

  Fly    64 FSTKVEITLAKETGIRWENLE--------------EAIVAAPVKPK---AKNWDQLVSEEEKIDE 111
            .||||||.|||...|.|.:||              .|:...||.|.   ||:||:|.:|.:| .|
plant   226 LSTKVEIRLAKAEIITWASLEYGKGQSVLPKPNVSSALSQRPVYPSSKPAKDWDKLEAEVKK-QE 289

  Fly   112 KEAK--GEAALTNLFKKIYSSSSPEVQKAMNKSFSESGGTVLSTNWNEVGKERVTVKPPNGTEFR 174
            |:.|  |:||:...|..||||:..::::||||||:||.||||||||.|||.::|...||:|.|.:
plant   290 KDEKLDGDAAMNKFFSDIYSSADEDMRRAMNKSFAESNGTVLSTNWKEVGTKKVESTPPDGMELK 354

  Fly   175 EWE 177
            :||
plant   355 KWE 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgt1	NP_649783.2	p23_CS_SGT1_like	6..84	CDD:107223	25/82 (30%)
Sgt1	NP_649783.2	SGS	97..176	CDD:282811	41/80 (51%)
SGT1B	NP_192865.1	PLN03088	1..358	CDD:215568	77/198 (39%)
		TPR repeat	2..30	CDD:276809
		TPR repeat	35..65	CDD:276809
		TPR repeat	70..95	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	88	1.000	Domainoid score	I2718
eggNOG	1	0.900	-	-		E1_COG5091
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4877
Inparanoid	1	1.050	132	1.000	Inparanoid score	I1865
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426397at2759
OrthoFinder	1	1.000	-	-		FOG0004070
OrthoInspector	1	1.000	-	-		otm3211
orthoMCL	1	0.900	-	-		OOG6_102530
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2822
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.730