DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgt1 and git7

DIOPT Version :9

Sequence 1:	NP_649783.2	Gene:	Sgt1 / 40982	FlyBaseID:	FBgn0265101	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_595340.1	Gene:	git7 / 2540962	PomBaseID:	SPBC36.12c	Length:	379	Species:	Schizosaccharomyces pombe

Alignment Length:	197	Identity:	69/197 - (35%)
Similarity:	104/197 - (52%)	Gaps:	32/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VRHDWYQSETKVVITVLLKNAVDKNYAVEITQKRVHM---TADGYELDL---KLLHPIVVERSSY 61
            :|:||.|:...:.|.:..|...|::.::.:.:..:.:   ..||....|   .|...||.|:||:
pombe   184 IRYDWSQTSFSLNIDIYAKKVKDEDVSLLMEKNTLKIEIKLEDGSIFSLVLDPLYEEIVPEKSSF 248

  Fly    62 KAFSTKVEITLAKETG-IRWENLEEAIVAAP--------------------VKPKAKNWDQLVSE 105
            |.||:||||||.|:.. |:|    ||:|.:|                    .|.|||:||.|...
pombe   249 KLFSSKVEITLIKKVSEIKW----EALVKSPANNSVNVYAKDSNHSSASGNTKNKAKDWDSLAKL 309

  Fly   106 EEKIDEKEAKGEAALTNLFKKIYSSSSPEVQKAMNKSFSESGGTVLSTNWNEVGKERVTVKPPNG 170
            .: ::|.|..|||||.|||:.:|.::..:.::||.||::||.||.|||||.:|..:....|||.|
pombe   310 AD-LEEDEPTGEAALANLFQNLYKNADDDTRRAMMKSYTESNGTALSTNWKDVKSKTFETKPPQG 373

  Fly   171 TE 172
            .|
pombe   374 ME 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgt1	NP_649783.2	p23_CS_SGT1_like	6..84	CDD:107223	27/84 (32%)
Sgt1	NP_649783.2	SGS	97..176	CDD:282811	34/76 (45%)
git7	NP_595340.1	SGT1	1..379	CDD:227422	69/197 (35%)
		p23_CS_SGT1_like	187..271	CDD:107223	28/87 (32%)
		SGS	301..379	CDD:282811	34/76 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	74	1.000	Domainoid score	I2523
eggNOG	1	0.900	-	-		E1_COG5091
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I1592
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004070
OrthoInspector	1	1.000	-	-		oto100530
orthoMCL	1	0.900	-	-		OOG6_102530
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R491
SonicParanoid	1	1.000	-	-		X2822
TreeFam	1	0.960	-	-
	11	10.750