DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgt1 and Cacybp

DIOPT Version :9

Sequence 1:	NP_649783.2	Gene:	Sgt1 / 40982	FlyBaseID:	FBgn0265101	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_033916.1	Gene:	Cacybp / 12301	MGIID:	1270839	Length:	229	Species:	Mus musculus

Alignment Length:	164	Identity:	45/164 - (27%)
Similarity:	65/164 - (39%)	Gaps:	46/164 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HDWYQSETKVVITVLLKNAVDKNYAVEITQKRVHMTADGYELDLK-------------LLHPIVV 56
            :.|.||:..|.|.:.|...    :.|.....:||.|...::|.:|             ||.||.|
Mouse    79 YGWDQSDKFVKIYITLTGV----HQVPTENVQVHFTERSFDLLVKNLNGKNYSMIVNNLLKPISV 139

  Fly    57 ERSSYKAFSTKVEITLAKETGIRWENLEEAIVAAPVKPKAKN--WDQLVSEEEKIDEK------- 112
            |.||.|..:..|.|...|                    ||:|  ||.|...|::..||
Mouse   140 ESSSKKVKTDTVIILCRK--------------------KAENTRWDYLTQVEKECKEKEKPSYDT 184

  Fly   113 EAKGEAALTNLFKKIYSSSSPEVQKAMNKSFSES 146
            ||.....|.|:.||||.....::::.:||::.||
Mouse   185 EADPSEGLMNVLKKIYEDGDDDMKRTINKAWVES 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgt1	NP_649783.2	p23_CS_SGT1_like	6..84	CDD:107223	24/90 (27%)
Sgt1	NP_649783.2	SGS	97..176	CDD:282811	19/59 (32%)
Cacybp	NP_033916.1	Interaction with SIAH1. /evidence=ECO:0000250	2..81		0/1 (0%)
		Siah-Interact_N	5..76	CDD:286164
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..60
		Interaction with SKP1. /evidence=ECO:0000250	74..229		45/164 (27%)
		p23_CacyBP	76..168	CDD:107225	29/112 (26%)
		Interaction with S100A6	155..229		22/84 (26%)
		SGS	183..>218	CDD:282811	10/34 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910