DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nac and SLC35C1

DIOPT Version :9

Sequence 1:	NP_649782.1	Gene:	nac / 40981	FlyBaseID:	FBgn0265351	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_060859.4	Gene:	SLC35C1 / 55343	HGNCID:	20197	Length:	364	Species:	Homo sapiens

Alignment Length:	316	Identity:	164/316 - (51%)
Similarity:	226/316 - (71%)	Gaps:	1/316 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LKIFFVVSLYWCTSILTVFVNKHLLSSDTVNLGAPLFMSWFQCVVSTVICFVASRLSRKYPSVFT 80
            |:|..||||||.|||..||:||:||.|.::.|..|:|::::||:|:|::|...|.|:...|....
Human    39 LQIALVVSLYWVTSISMVFLNKYLLDSPSLRLDTPIFVTFYQCLVTTLLCKGLSALAACCPGAVD 103

  Fly    81 FPEGNPLDIDTFRKILPLSVLYTLMIGANNLSLSYVTVAFYYIGRSLTTVFSVVLTYVILRQRTS 145
            ||... ||:...|.:|||||::..||..|||.|.||.||||.:||||||||:|:|:|::|:|.||
Human   104 FPSLR-LDLRVARSVLPLSVVFIGMITFNNLCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTS 167

  Fly   146 FKCLLCCGAIVVGFWLGVDQESLTEVFSWRGTIFGVLSSLALAMFSIQTKKSLGYVNQEVWLLSY 210
            |..||.||.|:.|||||||||......||.||:||||:||.:::.:|.|.|.|..|:..:|.|::
Human   168 FYALLTCGIIIGGFWLGVDQEGAEGTLSWLGTVFGVLASLCVSLNAIYTTKVLPAVDGSIWRLTF 232

  Fly   211 YNNLYSTLLFLPLIIINGELESIITYPHLWASWFWAAMTLSGLCGFAIGFVTALEIKVTSALTHN 275
            |||:.:.:|||||:::.|||:::..:..|.::.||..|||.||.|||||:||.|:||.||.||||
Human   233 YNNVNACILFLPLLLLLGELQALRDFAQLGSAHFWGMMTLGGLFGFAIGYVTGLQIKFTSPLTHN 297

  Fly   276 ISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRS 331
            :|||||||||||:|..||.:.:|.||||||::||..|:|||.|:..||.:..::.|
Human   298 VSGTAKACAQTVLAVLYYEETKSFLWWTSNMMVLGGSSAYTWVRGWEMKKTPEEPS 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nac	NP_649782.1	TPT	16..281	CDD:281186	136/264 (52%)
SLC35C1	NP_060859.4	EamA	42..183	CDD:304911	72/141 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149485
Domainoid	1	1.000	278	1.000	Domainoid score	I1716
eggNOG	1	0.900	-	-		E1_KOG1442
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41258
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2471
Isobase	1	0.950	-	0	Normalized mean entropy	S1961
OMA	1	1.010	-	-		QHG54539
OrthoDB	1	1.010	-	-		D356503at33208
OrthoFinder	1	1.000	-	-		FOG0005416
OrthoInspector	1	1.000	-	-		oto90630
orthoMCL	1	0.900	-	-		OOG6_104078
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1898
SonicParanoid	1	1.000	-	-		X1680
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750