DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nac and Slc35c1

DIOPT Version :9

Sequence 1:	NP_649782.1	Gene:	nac / 40981	FlyBaseID:	FBgn0265351	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001101218.1	Gene:	Slc35c1 / 311204	RGDID:	1309463	Length:	363	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	165/326 - (50%)
Similarity:	233/326 - (71%)	Gaps:	1/326 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EHNRLVNKYLKIFFVVSLYWCTSILTVFVNKHLLSSDTVNLGAPLFMSWFQCVVSTVICFVASRL 71
            |:...:.:.|:|..||||||.|||..||:||:||.|.::.|..|:|::::||:|::::|...|.|
  Rat    29 ENKPFLLRALQIALVVSLYWVTSISMVFLNKYLLDSPSLQLDTPIFVTFYQCLVTSLLCKGLSTL 93

  Fly    72 SRKYPSVFTFPEGNPLDIDTFRKILPLSVLYTLMIGANNLSLSYVTVAFYYIGRSLTTVFSVVLT 136
            :...|.:..||..| ||:...|.:|||||::..||..|||.|.||.||||.:||||||||:|:|:
  Rat    94 ATCCPGMVDFPTLN-LDLKVARSVLPLSVVFIGMITFNNLCLKYVGVAFYNVGRSLTTVFNVLLS 157

  Fly   137 YVILRQRTSFKCLLCCGAIVVGFWLGVDQESLTEVFSWRGTIFGVLSSLALAMFSIQTKKSLGYV 201
            |::|:|.|||..||.|..|:.|||||:|||......|..|||||||:||.:::.:|.|||.|..|
  Rat   158 YLLLKQTTSFYALLTCAIIIGGFWLGIDQEGAEGTLSLTGTIFGVLASLCVSLNAIYTKKVLPAV 222

  Fly   202 NQEVWLLSYYNNLYSTLLFLPLIIINGELESIITYPHLWASWFWAAMTLSGLCGFAIGFVTALEI 266
            :..:|.|::|||:.:.:|||||:::.|||.:::.:.||.::.||..|||.||.|||||:||.|:|
  Rat   223 DHSIWRLTFYNNVNACVLFLPLMVVLGELHALLAFAHLNSAHFWVMMTLGGLFGFAIGYVTGLQI 287

  Fly   267 KVTSALTHNISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRS 331
            |.||.||||:|||||||||||:|..||.:::|.||||||::||..|:|||.|:..||.:..:..|
  Rat   288 KFTSPLTHNVSGTAKACAQTVLAVLYYEEIKSFLWWTSNLMVLGGSSAYTWVRGWEMQKTQEDPS 352

  Fly   332 T 332
            :
  Rat   353 S 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nac	NP_649782.1	TPT	16..281	CDD:281186	136/264 (52%)
Slc35c1	NP_001101218.1	TPT	38..302	CDD:281186	136/264 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343361
Domainoid	1	1.000	280	1.000	Domainoid score	I1609
eggNOG	1	0.900	-	-		E1_KOG1442
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41258
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2346
OMA	1	1.010	-	-		QHG54539
OrthoDB	1	1.010	-	-		D356503at33208
OrthoFinder	1	1.000	-	-		FOG0005416
OrthoInspector	1	1.000	-	-		oto97740
orthoMCL	1	0.900	-	-		OOG6_104078
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1680
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810