Protein Alignment ato and HAND2

DIOPT Version :10

• Sequence 1: NP_731223.1
• Gene: ato / 40975
• FlyBaseID: FBgn0010433
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 48/152 - (31%)
• Similarity: 68/152 - (44%)
• Gaps: 17/152 - (11%)

  Fly   162 PSTTATSTPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDL 226
            |...|.:...|||.|..|      ..:|..|....:....:...:..|..|...::.......|.
Human    19 PFAAAAAAAAAAAASRCS------HEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDH 77

  Fly   227 A--DGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDR 289
            :  .|....|...|.|..|      ||   |||..||.:||||.|::|.||..||:.:|.:..|.
Human    78 SHYGGVPPGAGPPGLGGPR------PV---KRRGTANRKERRRTQSINSAFAELRECIPNVPADT 133

  Fly   290 QLSKHETLQMAQTYISALGDLL 311
            :|||.:||::|.:||:.|.|||
Human   134 KLSKIKTLRLATSYIAYLMDLL 155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	bHLH_TS_amos_like	250..311	CDD:381558	29/60 (48%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		18/48 (38%)
		bHLH_TS_HAND2	100..161	CDD:381477	28/56 (50%)