Protein Alignment ato and HAND2

DIOPT Version :9

• Sequence 1: NP_731223.1
• Gene: ato / 40975
• FlyBaseID: FBgn0010433
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 48/152 - (31%)
• Similarity: 68/152 - (44%)
• Gaps: 17/152 - (11%)

  Fly   162 PSTTATSTPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDL 226
            |...|.:...|||.|..|      ..:|..|....:....:...:..|..|...::.......|.
Human    19 PFAAAAAAAAAAAASRCS------HEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDH 77

  Fly   227 A--DGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDR 289
            :  .|....|...|.|..|      ||   |||..||.:||||.|::|.||..||:.:|.:..|.
Human    78 SHYGGVPPGAGPPGLGGPR------PV---KRRGTANRKERRRTQSINSAFAELRECIPNVPADT 133

  Fly   290 QLSKHETLQMAQTYISALGDLL 311
            :|||.:||::|.:||:.|.|||
Human   134 KLSKIKTLRLATSYIAYLMDLL 155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	29/59 (49%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		18/48 (38%)
		bHLH_TS_HAND2	100..161	CDD:381477	28/56 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910