DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ato and ATOH8

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	XP_011531441.1	Gene:	ATOH8 / 84913	HGNCID:	24126	Length:	328	Species:	Homo sapiens

Alignment Length:	197	Identity:	52/197 - (26%)
Similarity:	77/197 - (39%)	Gaps:	69/197 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 PAIPVASPPAVEVMGSSNVGTCKTIPA-SAGPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLY 183
            |.|.:.:|||              .|| ||.|.|...     ..||...:.||...|||.|
Human   152 PRILLCAPPA--------------RPAPSAPPAPPAP-----PESTVRPAPPTRPGESSYS---- 193

  Fly   184 TEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQI 248
              ...:..::|                                    :||::|  |.:||.|:..
Human   194 --SISHVIYNN------------------------------------HQDSSA--SPRKRPGEAT 218

  Fly   249 T-----PVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALG 308
            .     ..:::.|||.||||||.|:..::.||:.||:.:||....::|||...|::|..||.:|.
Human   219 AASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLA 283

  Fly   309 DL 310
            .|
Human   284 RL 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	25/58 (43%)
ATOH8	XP_011531441.1	HLH	231..282	CDD:278439	23/50 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910