Protein Alignment ato and TCF4

DIOPT Version :9

• Sequence 1: NP_731223.1
• Gene: ato / 40975
• FlyBaseID: FBgn0010433
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_001230155.2
• Gene: TCF4 / 6925
• HGNCID: 11634
• Length: 773
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 91/494 - (18%)
• Similarity: 153/494 - (30%)
• Gaps: 198/494 - (40%)

  Fly     4 SEIYRY---------YYKTSEDLQGFKTAAAEPYFNPMAAYNPGVTHYQFNGNTLASSSNYLSAN 59
            |:.|:|         .:.::.::|..|.....|.. |.:.|.|..:...:|.::....|:..:.:
Human   248 SQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL-PSSVYAPSASTADYNRDSPGYPSSKPATS 311

  Fly    60 GFIS--FEQ---ASSDGWISSS------------PASHRSESPEY----------------VDLN 91
            .|.|  |.|   .|||.|.|||            .:||..:|..|                .|:|
Human   312 TFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADIN 376

  Fly    92 -------TMYNGGCNN-----------------------MAQNQQYGMIMEQSVV---------- 116
                   |.:..|.|:                       .|.:.|.|..:.:::.
Human   377 SSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNN 441

  Fly   117 --STAPAIPVASPPAVE---VMGSSNVGTCKTIPASAGPKPKRS--------------YTKKNQP 162
              |:.|:.||.|||::.   .:.|.|.|...:.|...||.....              :..:|..
Human   442 SFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHA 506

  Fly   163 STTATSTP-----------------------------TAAAESSASVNLYTE------------- 185
            ...:|:.|                             .:|...|..|..:.|
Human   507 VGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLP 571

  Fly   186 --------------------------------EFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFD 218
                                            :.|:....:|.:..|. |.||:|......||..
Human   572 NQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDD-EGDENLQDTKSSEDKK 635

  Fly   219 GNDGSFDL-----ADGENQDAAAGGSGKKRRGKQITPVVK----RKRRLAANARERRRMQNLNQA 274
            .:|...|:     :...|.|           .:.:||..|    ::||:|.|||||.|::::|:|
Human   636 LDDDKKDIKSITRSRSSNND-----------DEDLTPEQKAEREKERRMANNARERLRVRDINEA 689

  Fly   275 FDRLRQYLPC-LGNDRQLSKHETLQMAQTYISALGDLLR 312
            |..|.:.:.. |.:|:..:|...|..|...|.:|...:|
Human   690 FKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVR 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	21/63 (33%)
TCF4	NP_001230155.2	HLH	676..729	CDD:197674	18/53 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910