DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and Neurod2

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_062199.2	Gene:	Neurod2 / 54276	RGDID:	3166	Length:	382	Species:	Rattus norvegicus

Alignment Length:	201	Identity:	61/201 - (30%)
Similarity:	80/201 - (39%)	Gaps:	70/201 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 PVASPPAVEVMGSSNVGTCKTIPASAGPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLYTEEF 187
            |...|||               |.|..|.|.|: ||...........||.|
  Rat    37 PPQPPPA---------------PGSGAPGPARA-TKPVSLRGEEVPEPTLA-------------- 71

  Fly   188 QNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPVV 252
                         .|:::.:|    |||:.:..:      :.|..|.|.|...|||..|
  Rat    72 -------------EVKEEGEL----GGEEEEEEE------EEEGLDEAEGERPKKRGPK------ 107

  Fly   253 KRK-----------RRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISA 306
            |||           ||..||||||.||.:||.|.|.||:.:||....::|||.|||::|:.||.|
  Rat   108 KRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWA 172

  Fly   307 LGDLLR 312
            |.::||
  Rat   173 LSEILR 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	32/69 (46%)
Neurod2	NP_062199.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..129		34/150 (23%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	42/103 (41%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		4/11 (36%)
		Neuro_bHLH	180..310	CDD:403655
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910