DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and Atoh8

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001102711.1	Gene:	Atoh8 / 500200	RGDID:	1561512	Length:	322	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	49/213 - (23%)
Similarity:	76/213 - (35%)	Gaps:	63/213 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 STAPAIPVASPPAVE---VMGSSNVGTCK-----------TIPASAGPKPKRSYTKKNQPSTTAT 167
            :..|.:|...||...   ..|...|...:           ..||...|....:.....|.|....
  Rat   118 TVGPGLPTPPPPPASQSLAPGDPEVQPLREQALRPRILLCAPPARPTPSAPLAPPAVPQESPVRP 182

  Fly   168 STPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQ 232
            :.||...|||.|      ...:..::|                                    :.
  Rat   183 APPTRPGESSYS------SISHVIYNN------------------------------------HP 205

  Fly   233 DAAAGGSGKKRRGKQIT-----PVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLS 292
            |::|  |.:||.|:...     ..:::.|||.||||||.|:..::.||:.||:.:||....::||
  Rat   206 DSSA--SPRKRPGEATAASTEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLS 268

  Fly   293 KHETLQMAQTYISALGDL 310
            |...|::|..||.:|..|
  Rat   269 KLAILRIACNYILSLARL 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	25/58 (43%)
Atoh8	NP_001102711.1	HLH	232..283	CDD:278439	23/50 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910