Protein Alignment ato and NEUROD2

DIOPT Version :9

• Sequence 1: NP_731223.1
• Gene: ato / 40975
• FlyBaseID: FBgn0010433
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_006151.3
• Gene: NEUROD2 / 4761
• HGNCID: 7763
• Length: 382
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 58/196 - (29%)
• Similarity: 78/196 - (39%)
• Gaps: 60/196 - (30%)

  Fly   123 PVASPPAVEVMGSSNVGTCKTIPASAGPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLYTEEF 187
            |...|||               |....|.|.|:  .|..|......|....||......|..||
Human    37 PPPPPPA---------------PGPGAPGPARA--AKPVPLRGEEGTEATLAEVKEEGELGGEE- 83

  Fly   188 QNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPVV 252
                       ::..|::|.|                |.|:||.         .|:||.:...:.
Human    84 -----------EEEEEEEEGL----------------DEAEGER---------PKKRGPKKRKMT 112

  Fly   253 KRK------RRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLL 311
            |.:      ||..||||||.||.:||.|.|.||:.:||....::|||.|||::|:.||.||.::|
Human   113 KARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL 177

  Fly   312 R 312
            |
Human   178 R 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	30/64 (47%)
NEUROD2	NP_006151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		31/145 (21%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	42/116 (36%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		0/5 (0%)
		Neuro_bHLH	180..310	CDD:403655

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840