DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and MYOD1

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_002469.2	Gene:	MYOD1 / 4654	HGNCID:	7611	Length:	320	Species:	Homo sapiens

Alignment Length:	154	Identity:	46/154 - (29%)
Similarity:	61/154 - (39%)	Gaps:	39/154 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 TEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGN----------------DGSFDLADGENQ 232
            |::|          :||...|..||..|   ||.|..                ..:...|.|..:
Human    26 TDDF----------YDDPCFDSPDLRFF---EDLDPRLMHVGALLKPEEHSHFPAAVHPAPGARE 77

  Fly   233 DA-AAGGSGKKRRGKQI---TPVVKRK-----RRLAANARERRRMQNLNQAFDRLRQYLPCLGND 288
            |. ....||..:.|:.:   ....|||     ||.||..|||||:..:|:||:.|::......|.
Human    78 DEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQ 142

  Fly   289 RQLSKHETLQMAQTYISALGDLLR 312
            | |.|.|.|:.|..||..|..|||
Human   143 R-LPKVEILRNAIRYIEGLQALLR 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	27/63 (43%)
MYOD1	NP_002469.2	BASIC	19..114	CDD:128794	22/100 (22%)
		bHLH_TS_MYOD1_Myf3	105..165	CDD:381506	24/60 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..219
		Myf5	191..259	CDD:403446
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910