DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and ASCL2

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_005161.1	Gene:	ASCL2 / 430	HGNCID:	739	Length:	193	Species:	Homo sapiens

Alignment Length:	88	Identity:	31/88 - (35%)
Similarity:	44/88 - (50%)	Gaps:	14/88 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 GSGKKRR--GKQITPVVKRKRRLAA------------NARERRRMQNLNQAFDRLRQYLPCLGND 288
            |...:||  ..::....:|:|...|            |.|||.|::.:|..|..|||::|..|..
Human    19 GCAARRRPASPELLRCSRRRRPATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGAS 83

  Fly   289 RQLSKHETLQMAQTYISALGDLL 311
            ::|||.|||:.|..||.||..||
Human    84 KKLSKVETLRSAVEYIRALQRLL 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	28/71 (39%)
ASCL2	NP_005161.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..56		3/18 (17%)
		HLH	66..108	CDD:197674	20/41 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..177
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910