DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and neurog1

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_571116.1	Gene:	neurog1 / 30239	ZFINID:	ZDB-GENE-990415-174	Length:	208	Species:	Danio rerio

Alignment Length:	114	Identity:	45/114 - (39%)
Similarity:	56/114 - (49%)	Gaps:	22/114 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 DGSFDLADGENQDAA-----------------AGGSGKKR-----RGKQITPVVKRKRRLAANAR 263
            |.||...|.|:..::                 ||...|||     |.:....|||:.|||.||.|
Zfish    14 DYSFSHTDDEDSRSSLHPASPASSCGKPPASPAGLQQKKRRRGRARNETTVHVVKKNRRLKANDR 78

  Fly   264 ERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLLR 312
            ||.||.|||.|.|.||..||...:|.:|:|.|||:.|..||.||.:.:|
Zfish    79 ERNRMHNLNDALDALRSVLPAFPDDTKLTKIETLRFAHNYIWALSETIR 127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	31/58 (53%)
neurog1	NP_571116.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62		11/47 (23%)
		CCDC106	<20..>102	CDD:292422	30/81 (37%)
		HLH	68..127	CDD:238036	31/58 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..180
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840