DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ato and ATOH7

DIOPT Version :9

Sequence 1:NP_731223.1 Gene:ato / 40975 FlyBaseID:FBgn0010433 Length:312 Species:Drosophila melanogaster
Sequence 2:NP_660161.1 Gene:ATOH7 / 220202 HGNCID:13907 Length:152 Species:Homo sapiens


Alignment Length:85 Identity:43/85 - (50%)
Similarity:53/85 - (62%) Gaps:8/85 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   227 ADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQL 291
            |.|........|:|:....        .:||||||||||||||.||.||||||:.:|..|.|::|
Human    20 AGGTECAGTCAGAGRLESA--------ARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKL 76

  Fly   292 SKHETLQMAQTYISALGDLL 311
            ||:||||||.:||.||..:|
Human    77 SKYETLQMALSYIMALTRIL 96

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
atoNP_731223.1 HLH 253..312 CDD:238036 39/59 (66%)
ATOH7NP_660161.1 bHLH_TS_ATOH7 34..102 CDD:381557 39/71 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165145415
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19290
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2611
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.870

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