DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and Ptf1a

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_061279.2	Gene:	Ptf1a / 19213	MGIID:	1328312	Length:	324	Species:	Mus musculus

Alignment Length:	284	Identity:	73/284 - (25%)
Similarity:	110/284 - (38%)	Gaps:	90/284 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FNGNTLASSSNYLSANGFISFEQAS------SDGWISSSPA-----SHRSESPEYVDLNTMYNGG 97
            |.|......|.|.....|.: :|:|      ||..:....|     ||:.....|.|      |.
Mouse     9 FPGGLDTFPSPYFDEEDFFT-DQSSRDPLEDSDELLGDEQAEVEFLSHQLHEYCYRD------GA 66

  Fly    98 CNNMAQNQQYGMIMEQSVVSTAPAIPVASPPAVEVMG--SSNVGTC--KTIPASAGPKPKRSYTK 158
            |           ::.|...|.||  ...:||.:...|  ..||..|  ...|.:|.|     |:.
Mouse    67 C-----------LLLQPAPSAAP--HALAPPPLGDPGEPEDNVSYCCDAGAPLAAFP-----YSP 113

  Fly   159 KNQPSTTATSTPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGS 223
            .:.||..|  .|.||                                    :.|.|....|.:|:
Mouse   114 GSPPSCLA--YPCAA------------------------------------VLSPGARLGGLNGA 140

  Fly   224 FDLADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGND 288
                      |||..:.::||.:....:  ::.|.|||.|||||||::|.||:.||.::|.|..:
Mouse   141 ----------AAAAAARRRRRVRSEAEL--QQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYE 193

  Fly   289 RQLSKHETLQMAQTYISALGDLLR 312
            ::|||.:||::|..||:.|.:|::
Mouse   194 KRLSKVDTLRLAIGYINFLSELVQ 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	28/58 (48%)
Ptf1a	NP_061279.2	HLH	162..217	CDD:238036	28/54 (52%)
Ptf1a	NP_061279.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910