DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and Lyl1

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_032561.2	Gene:	Lyl1 / 17095	MGIID:	96891	Length:	278	Species:	Mus musculus

Alignment Length:	241	Identity:	64/241 - (26%)
Similarity:	88/241 - (36%)	Gaps:	77/241 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 AQNQQYGMIMEQSVVSTAPAIPVAS------------------PPAVEVMGSSNVGTCKTIPASA 148
            |..::..|:...|.....|:.|.:.                  ||.|.|:   |:|..:.|.| |
Mouse    13 AMTEKTEMVCASSPAPAPPSKPASPGPLSTEEVDHRNTCTPWLPPGVPVI---NLGHTRPIGA-A 73

  Fly   149 GPKPKRSYTKKNQPSTTA--TSTPTAAAESSASVNLYTEEFQN---------FD-FDNSALFDDS 201
            .|..:.|..:.:....||  .:.||.|      |:.:...|.|         |. |.||.|
Mouse    74 MPTTELSAFRPSLLQLTALGRAPPTLA------VHYHPHPFLNSVYIGPAGPFSIFPNSRL---- 128

  Fly   202 VEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERR 266
                          ....:....|||||......|                   ||:..|:|||.
Mouse   129 --------------KRRPSHSELDLADGHQPQKVA-------------------RRVFTNSRERW 160

  Fly   267 RMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLLR 312
            |.|::|.||..||:.||....||:|||:|.|::|..||..|..|||
Mouse   161 RQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLR 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	27/58 (47%)
Lyl1	NP_032561.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46		5/32 (16%)
		bHLH_TS_LYL1	145..209	CDD:381548	30/81 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..278
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910