DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ato and AgaP_AGAP001741

DIOPT Version :9

Sequence 1:	NP_731223.1	Gene:	ato / 40975	FlyBaseID:	FBgn0010433	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	XP_321345.3	Gene:	AgaP_AGAP001741 / 1281434	VectorBaseID:	AGAP001741	Length:	282	Species:	Anopheles gambiae

Alignment Length:	321	Identity:	113/321 - (35%)
Similarity:	157/321 - (48%)	Gaps:	63/321 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EDLQGFKTAAAEPYFNPMAAYNPGVTHYQFNGNTL----ASSSNYLSANG------FISFEQASS 69
            |.|:...:.|...|.|         ::|.:..||:    |:|:|.::.:.      ...|.....
Mosquito     2 EQLEVPSSLAESSYLN---------SNYSYASNTVTTTSANSTNLVAQSAAPNVVILPGFMDNYP 57

  Fly    70 DGWISSSPASHRSESPEYVDLNTMYNGGCNNMAQNQQYGMIMEQSVVSTAPA------IPVASPP 128
            |.|::.||:|..||||:|..|.........::.:.::..|.|:|...|..|:      :|::.||
Mosquito    58 DSWMTPSPSSFGSESPDYYSLANSPQRSFVDVEEYKENLMAMQQQKPSQLPSLLPSAILPLSPPP 122

  Fly   129 AVEVMGSSNV----GTCKTIPASAG-PKPKRSYTKKNQPSTTATSTPTAAAESSAS--VNLYTEE 186
            ...:....:|    ..|.|.|.:.. |..||.|.:|.:    |...|.:.||:.|:  .:|....
Mosquito   123 PAPLATVQSVHPASNGCSTSPPTTNLPVKKRQYNRKPK----AKPEPPSGAETDATSRADLSCLT 183

  Fly   187 FQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPV 251
            |....|..:|                     |.|:     ...|....|.|..||::| ||:.|.
Mosquito   184 FPKSLFPRAA---------------------DPNN-----VHSEGTTGAVGVIGKRKR-KQVPPQ 221

  Fly   252 VKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLLR 312
            :|:|||||||||||:||||||.||||||||||.||||||||||||||||||||:||.|||:
Mosquito   222 IKKKRRLAANARERKRMQNLNDAFDRLRQYLPSLGNDRQLSKHETLQMAQTYITALCDLLQ 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ato	NP_731223.1	HLH	253..312	CDD:238036	52/58 (90%)
AgaP_AGAP001741	XP_321345.3	HLH	223..282	CDD:238036	52/58 (90%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	98	1.000	Domainoid score	I13510
eggNOG	1	0.900	-	-		E1_KOG4395
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H138375
Inparanoid	1	1.050	146	1.000	Inparanoid score	I6850
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D124435at33392
OrthoFinder	1	1.000	-	-		FOG0000894
OrthoInspector	1	1.000	-	-		oto109194
Panther	1	1.100	-	-	LDO	PTHR19290
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X15876
TreeFam	0	0.000	Not matched by this tool.
	11	10.970