Protein Alignment CG9630 and SPB4

DIOPT Version :9

• Sequence 1: NP_649777.1
• Gene: CG9630 / 40974
• FlyBaseID: FBgn0037561
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_116654.1
• Gene: SPB4 / 850549
• SGDID: S000001894
• Length: 606
• Species: Saccharomyces cerevisiae
• Alignment Length: 647
• Identity: 217/647 - (33%)
• Similarity: 342/647 - (52%)
• Gaps: 87/647 - (13%)

  Fly     8 SLDKPPLSDAVLQVVQS----FGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLE- 67
            ||:...|..::|..:::    .||:.|||||.:.||:|...|||..::|||||||.||::|:||
Yeast     4 SLEWDNLGFSLLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVTGSGKTAAFVIPVLEK 68

  Fly    68 ILQRRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEH--EDLEHLNQQLIVGGN--SIEED 128
            :::.....:.:......:|:|:|||||:|||..|:..||||  .||..:..||:||.|  ::.:|
Yeast    69 VVKEEANTSKFKKAHFHSLIIAPTRELSRQIESVVLSFLEHYPSDLFPIKCQLLVGTNEATVRDD 133

  Fly   129 IATLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGY 193
            ::...|..|.||:.||||:.|..|..      |.:..:...:|:||||||||:.|......||..
Yeast   134 VSNFLRNRPQILIGTPGRVLDFLQMP------AVKTSACSMVVMDEADRLLDMSFIKDTEKILRL 192

  Fly   194 LPRQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEF 258
            ||:||||||||||..:..:|:.:.||||||.::|..|.  ..|:.|:..|.:|.|..|...|:..
Yeast   193 LPKQRRTGLFSATMRSAGSDIFKTGLRNPVRITVNSKN--QAPSSLKLNYCVVNPAEKLQLLVSI 255

  Fly   259 LSSPATVIGKVMVFFPTCACVEYWAEALPPLLPKRTVL-------GIHGKMK-NKRANVVEKFRN 315
            |::  ....|.:|:||||..|.|:...: ..|.||.:|       .:|||:: :.|...:..|.:
Yeast   256 LNN--YKFKKCIVYFPTCVSVSYFYSFI-QYLGKRNILVNEVEIFSLHGKLQTSARTKTLTAFTD 317

  Fly   316 T-PQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPS-EDAY 378
            : ..:||..|||.|||:|:|:::.|:|.|||:....|:||.|||.|....|.|:.||... |:.:
Yeast   318 SLSNSVLFTTDVAARGIDIPDVDLVIQLDPPTNTDMFMHRCGRTGRANRVGKAITFLNEGREEDF 382

  Fly   379 VHFLKINQKVELTKLLTEEAEDADREKKKLPA-VLDQLHRLQAADKGVYDKGMRAFVSHVRAYTK 442
            :.|::: :.|||        |:.|.|.|.:.. ..:........|:..:|||::|:|:.::.|:.
Yeast   383 IPFMQV-KNVEL--------EELDLEVKGITTNFYEDFRNWILEDRDRFDKGVKAYVAFIKYYSN 438

  Fly   443 HECSAILRLKDLDLGKMATAYGLLQLPRMPELKNY----------QGGGYVAPAFEVDLSKLTYK 497
            |..::|.||:.||...:|..|||.:||||||:..|          .|...|.|  .|::.:..||
Yeast   439 HSATSIFRLQSLDYVGIAKLYGLFRLPRMPEITKYLATEKQEGIFPGNWLVDP--PVNMDEYKYK 501

  Fly   498 NAQKEQVRQKKMETYEQTGSWPGQKQH-KKRVESWDQ---TKKAKLDAKSKKELRKAKKQRKKAA 558
            :.::|:.||:.::...........|.. ||:..:|..   ||:.||:.|.|..|      ::||.
Yeast   502 DKKREKERQETLKNISLINDKKKLKSELKKKNLAWSDKTLTKERKLERKEKMSL------KRKAI 560

  Fly   559 EAEASRSGKGKKRQQFSQEDLDELASDIRL---FKRL----KKNKISEEDFDKAMGIEGNND 613
            |            ::...|:|||.|.:.|:   :|.:    |:.|:|.:      .|:||.|
Yeast   561 E------------EELKAEELDENAEEERIKEDWKEIVLQNKRKKVSSK------AIQGNFD 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	94/226 (42%)
		DEXDc	22..232	CDD:214692	92/218 (42%)
		HELICc	239..370	CDD:238034	48/139 (35%)
		DUF4217	411..470	CDD:290667	18/58 (31%)
SPB4	NP_116654.1	SrmB	1..>383	CDD:223587	148/389 (38%)
		DUF4217	409..466	CDD:404785	18/56 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345857
Domainoid	1	1.000	141	1.000	Domainoid score	I1016
eggNOG	1	0.900	-	-		E2759_KOG0345
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12196
Inparanoid	1	1.050	307	1.000	Inparanoid score	I484
Isobase	1	0.950	-	0	Normalized mean entropy	S1206
OMA	1	1.010	-	-		QHG53613
OrthoFinder	1	1.000	-	-		FOG0003582
OrthoInspector	1	1.000	-	-		oto100053
orthoMCL	1	0.900	-	-		OOG6_102339
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1376
SonicParanoid	1	1.000	-	-		X2452
TreeFam	1	0.960	-	-
	16	15.740