DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9630 and AT1G71280

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_177284.1	Gene:	AT1G71280 / 843469	AraportID:	AT1G71280	Length:	465	Species:	Arabidopsis thaliana

Alignment Length:	598	Identity:	203/598 - (33%)
Similarity:	282/598 - (47%)	Gaps:	162/598 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KWSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEIL 69
            ::|.| |||||:.:::.:...||:..||||...||.|.:.|||..:|.||||||||||:|.:||:
plant    16 RFSEL-KPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEII 79

  Fly    70 QRRHKETPWGPKEIGALVISPTRELARQISEVL-AQFLEHEDLEHLNQQLIVGGNSIEEDIATLR 133
             ||....|..|.::..::|||||||:.||.:|. |..|:....           ..:|.|:.||.
plant    80 -RRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKC-----------REVEADMNTLE 132

  Fly   134 RETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQR 198
            .|...:|:.|||||.|:.:|. :.|:.    ::||.|:|||||||||:||:..||.|:..||:||
plant   133 EEGANLLIGTPGRLSDMMKRM-EFLDF----RNLEILILDEADRLLDMGFQKQVNYIISRLPKQR 192

  Fly   199 RTGLFSATQTTEVTDLIRAGLRNPVL-VSVKEKASVNTPARLQNFYRIVEPELKFVALLEFLSSP 262
            ||||||||||..|.||.:||||||.| ....:|:|       |..:.::|.:.|
plant   193 RTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSS-------QLVHLLIENKNK----------- 239

  Fly   263 ATVIGKVMVFFPTCACVEYWAEALP--PLLPKRTVLGIHGKMKNK-RANVVEKFRNTPQAVLLCT 324
                 |::|||.|||||:||...:.  |.|...:....||||..| |...:..|......|||||
plant   240 -----KLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCT 299

  Fly   325 DVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVE 389
            ||.|||||:|.|                                        .|:..|.|.
plant   300 DVAARGLDIPGI----------------------------------------VYIRSLAIK---- 320

  Fly   390 LTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECSAILRLKDL 454
                        |||                    |.:||::||||.||||.:|:||.|...|.|
plant   321 ------------DRE--------------------VLEKGLKAFVSFVRAYKEHQCSYIFSWKGL 353

  Fly   455 DLGKMATAYGLLQLPRMPELKNYQGG--GYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGS 517
            ::||:|..||:|..|.:.|:|..:.|  |: .|...:....:.:||..:|:.||:.:
plant   354 EIGKLAMGYGILSFPYISEVKQDRIGIVGF-TPVQGITFEDIKFKNKSREKQRQQNL-------- 409

  Fly   518 WPGQKQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEA-----EASRSGK--GKKRQQFS 575
                                 |..|.|.:..|..|::|.:.||     :|||..|  |::||..
plant   410 ---------------------LARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTI- 452

  Fly   576 QEDLDELASDIRL 588
            |...||...::||
plant   453 QTAQDEEEMNLRL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	104/221 (47%)
		DEXDc	22..232	CDD:214692	98/211 (46%)
		HELICc	239..370	CDD:238034	37/133 (28%)
		DUF4217	411..470	CDD:290667	23/58 (40%)
AT1G71280	NP_177284.1	DEADc	17..217	CDD:238167	102/217 (47%)
		DEXDc	32..217	CDD:214692	95/201 (47%)
		Helicase_C	223..>314	CDD:278689	39/153 (25%)
		DUF4217	314..368	CDD:290667	28/89 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	164	1.000	Domainoid score	I1224
eggNOG	1	0.900	-	-		E2759_KOG0345
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12196
Inparanoid	1	1.050	398	1.000	Inparanoid score	I473
OMA	1	1.010	-	-		QHG53613
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	1	1.000	-	-		FOG0003582
OrthoInspector	1	1.000	-	-		otm2893
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24031
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2452
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.940