DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9630 and AT5G05450

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_196164.1	Gene:	AT5G05450 / 830428	AraportID:	AT5G05450	Length:	593	Species:	Arabidopsis thaliana

Alignment Length:	622	Identity:	242/622 - (38%)
Similarity:	361/622 - (58%)	Gaps:	59/622 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRKKWSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPM 65
            ::..::|.|: ||||..:::.:....|:..||||.|.||||.:.|||:.:|.|||||||||:||:
plant    11 LTETRFSDLE-PPLSGDIIEALNQSDFEFCTPVQAATIPLLCSYKDVAVDAATGSGKTLAFVVPL 74

  Fly    66 LEILQRRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGNSIEEDIA 130
            :||| ||....|..|.::..::|||||||:.||..|...|:  ..|.::|..|:|||..::.|:.
plant    75 VEIL-RRSTSFPPKPHQVMGVIISPTRELSTQIYNVAQPFV--STLANVNSVLLVGGREVKADMK 136

  Fly   131 TLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLP 195
            .:..|...:|:.|||||.|:.:|..     ....::||.|:||||||||::||:..||.|:..||
plant   137 IIEEEGCNVLIGTPGRLSDIMERME-----ILDFRNLEILILDEADRLLEMGFQRQVNYIISRLP 196

  Fly   196 RQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEKA---------SVNTPARLQNFYRIVEPELK 251
            :||||||||||||..|.:|.:|||||||.|.|:.|:         :..||:.|...|...|.:.|
plant   197 KQRRTGLFSATQTEGVEELAKAGLRNPVRVEVRAKSKSESSQQLTNSKTPSGLHLEYMECEADKK 261

  Fly   252 FVALLEFLSSPATVIGKVMVFFPTCACVEYWAEALP--PLLPKRTVLGIHGKMK-NKRANVVEKF 313
            ...|::.|...:.  .|::|||.|||.|:||...|.  |.|...:::.|||.|| |.|...:..|
plant   262 SSQLVDLLIKNSD--KKLIVFFMTCASVDYWGLVLSKIPALKSISLIPIHGDMKQNARDKALASF 324

  Fly   314 RNTPQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAY 378
            .......||||||.|||||:|.|::|||:|||...:.|.||.|||||.|.:|.|:|||||.|:||
plant   325 TKASSGALLCTDVAARGLDIPGIDYVVQYDPPQDPNMFNHRAGRTARLGRQGRAIVFLLPKEEAY 389

  Fly   379 VHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKH 443
            |.|::|.:.....:..:|:|.|          |:..:......|:.|.:||::||||.||||.:|
plant   390 VEFMRIRRVPLEERKCSEDASD----------VIPIIRSAAMKDRAVMEKGLKAFVSFVRAYKEH 444

  Fly   444 ECSAILRLKDLDLGKMATAYGLLQLPRMPELKNYQ--GGGYVAPAFEVDLSKLTYKNAQKEQVRQ 506
            .||.|.|.|||::||:|..||||.||.|.|:|.::  ..|: .|...|...::.:|:..:|:.||
plant   445 HCSFIFRWKDLEIGKLAMGYGLLYLPSMSEVKQHRLSSEGF-TPVEGVKFEEIKFKDKYREKQRQ 508

  Fly   507 KKMETYEQTGSWPGQKQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEAEASRSGKGKKR 571
            :.::.          ::.|::.|..::.|:.::||.:..:.:|            |||...||:|
plant   509 QNLQV----------RKEKRQEEKKEKGKRKRVDASASNDPKK------------ASRKLTGKQR 551

  Fly   572 QQF-SQEDLDELASDIRLFKRLKKNKISEEDFDKAMG 607
            |.. :.||.:.:..|.:|..::||..|.|:::::..|
plant   552 QTIQTAEDEEVMDRDYKLMIKVKKGLIKEDEYERLTG 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	104/219 (47%)
		DEXDc	22..232	CDD:214692	101/218 (46%)
		HELICc	239..370	CDD:238034	57/133 (43%)
		DUF4217	411..470	CDD:290667	29/58 (50%)
AT5G05450	NP_196164.1	SrmB	12..501	CDD:223587	217/510 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	164	1.000	Domainoid score	I1224
eggNOG	1	0.900	-	-		E2759_KOG0345
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12196
Inparanoid	1	1.050	398	1.000	Inparanoid score	I473
OMA	1	1.010	-	-		QHG53613
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	1	1.000	-	-		FOG0003582
OrthoInspector	1	1.000	-	-		otm2893
orthoMCL	1	0.900	-	-		OOG6_102339
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2452
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840