Protein Alignment CG9630 and DDX24

DIOPT Version :9

• Sequence 1: NP_649777.1
• Gene: CG9630 / 40974
• FlyBaseID: FBgn0037561
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_065147.1
• Gene: DDX24 / 57062
• HGNCID: 13266
• Length: 859
• Species: Homo sapiens
• Alignment Length: 736
• Identity: 177/736 - (24%)
• Similarity: 277/736 - (37%)
• Gaps: 261/736 - (35%)

  Fly     6 WSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAI-PLLLARKDVSAEAVTGSGKTLAFLVPMLEIL 69
            |..|..|   ..||:.:...||...||:|...: |.:..:.|:...|.|||||||||.:||:..:
Human   194 WKDLFVP---RPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAV 255

  Fly    70 ---QRR-------HKETPWG----------------------------------PKEIGA----- 85
               |:|       :.|.|.|                                  |.:|.|
Human   256 LQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPDDTVIESEALPSDIAAEARAK 320

  Fly    86 ----------------------------------------------------------------- 85
                                                                             
Human   321 TGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEENLDKEQTGNLKQELDDKSATCKAYPK 385

  Fly    86 -----LVISPTRELARQIS---EVLAQFLEHEDLEHLNQQLIVGGNSIEEDIATLRRETPCILVC 142
                 ||::||||||.|:.   :.:|:|      ..:...::|||.|.::....|.|. |.|:|.
Human   386 RPLLGLVLTPTRELAVQVKQHIDAVARF------TGIKTAILVGGMSTQKQQRMLNRR-PEIVVA 443

  Fly   143 TPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNIL------GYLPRQRRTG 201
            |||||.:|.:.|...|.   .::.|..||:|||||:::.|....::.:|      .|.|: |:|.
Human   444 TPGRLWELIKEKHYHLR---NLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK-RQTL 504

  Fly   202 LFSATQT--------------------TEVTDLI--RAGLR-NPVLVSV-KEKASVNTPARLQNF 242
            :||||.|                    |...||:  :.|:| .|.::.: :.:|:|.|   |...
Human   505 VFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVET---LTET 566

  Fly   243 YRIVEPELKFVALLEFLSS-PATVIGKVMVFFPTCACVEYWAEALPPL--LPKRTVLGIHGKMKN 304
            ....|.:.|...|..||.. |    |:.:||..:.:|::..:..|..|  :|    |.:|..|..
Human   567 KIHCETDEKDFYLYYFLMQYP----GRSLVFANSISCIKRLSGLLKVLDIMP----LTLHACMHQ 623

  Fly   305 K-RANVVEKFRNTPQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNAL 368
            | |...:|:|......|||.|||.|||||:|:::.|:.:..|.|:..:|||.|||||..|||.:|
Human   624 KQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSL 688

  Fly   369 VFLLPSEDAYVHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAF 433
            :.:.| ||. ::|.||.:.::           .|.:....|               |..|.|...
Human   689 MLIGP-EDV-INFKKIYKTLK-----------KDEDIPLFP---------------VQTKYMDVV 725

  Fly   434 VSHVRAYTKHECSAILRLKDLDLGKMATAYGLLQLPRMPELKNYQG---GGYV---APAFEVDLS 492
            ...:|...:.|.|                          |.:|:|.   ..::   |.|.|::|.
Human   726 KERIRLARQIEKS--------------------------EYRNFQACLHNSWIEQAAAALEIELE 764

  Fly   493 KLTYK----NAQKEQVRQKKME---------------TYEQTGSWPGQKQHKKRVESWDQTKKAK 538
            :..||    :.|:|:.|||:|:               |..|...:|.|......:.|.....::.
Human   765 EDMYKGGKADQQEERRRQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESA 829

  Fly   539 LDAKSKKELRKAKKQRKKAAE 559
            |...||::.:|.||.::...|
Human   830 LSCLSKQKKKKTKKPKEPQPE 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	85/371 (23%)
		DEXDc	22..232	CDD:214692	80/362 (22%)
		HELICc	239..370	CDD:238034	48/134 (36%)
		DUF4217	411..470	CDD:290667	6/58 (10%)
DDX24	NP_065147.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..170
		SrmB	191..783	CDD:223587	162/667 (24%)
		Q motif	192..220		9/28 (32%)
		P-loop_NTPase	194..511	CDD:304359	78/330 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..300		3/37 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	326..376		0/49 (0%)
		DEAD box	471..474		2/2 (100%)
		Helicase_C	573..681	CDD:278689	41/115 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	799..859		12/52 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010