DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9630 and ddx1

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001184253.1	Gene:	ddx1 / 556790	ZFINID:	ZDB-GENE-041001-215	Length:	740	Species:	Danio rerio

Alignment Length:	384	Identity:	106/384 - (27%)
Similarity:	155/384 - (40%)	Gaps:	82/384 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 TGSGKTLAFLVPMLEILQRRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQ 117
            |||.|.            .:.|.:...|:   ||:|.|::|||.|....:.||.::.|...|.:.
Zfish   272 TGSAKV------------TQVKSSSNAPR---ALIIEPSKELAEQTLNNVNQFKKYVDNPKLREL 321

  Fly   118 LIVGGNSIEEDIATLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLG 182
            ||:||.:.:|.:..|..... |:|.|||||:||......||   :||:   ||||||.|.||..|
Zfish   322 LIIGGVAAKEQLNVLESGVD-IVVGTPGRLDDLISTGKLDL---SQVR---FLVLDECDGLLSAG 379

  Fly   183 FKTSVNNILGYLPRQRRTG------LFSAT-QTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQ 240
            ....:..|...:|:....|      :.||| .:.:|..|....:..|..|.:|.:.||  |..:.
Zfish   380 NTDFIMRIYNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSV--PETVH 442

  Fly   241 NFYRIVEPELKFVALLEFLSSPATVIGKVMV---FFPTCACVEYWAEALPPLLPKRTVLGI---- 298
            :....|.|  |...|.|.|........:|..   ..|.....|.|:||:..|..:.||..|
Zfish   443 HVVVTVNP--KNDKLWERLGKNHIRTDEVHAKDDTRPGANSPEMWSEAIKILKGEYTVRAIKEHK 505

  Fly   299 ----------------------------------------HGKMK-NKRANVVEKFRNTPQAVLL 322
                                                    ||..| |:|...:|:|:......|:
Zfish   506 MDQAIIFCRTKIDCDNMEQYFIKQGGGPDKKGHQFSCVCLHGDRKPNERKYNLERFKKQEVKFLI 570

  Fly   323 CTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNAL-VFLLPSEDAYVH 380
            ||||.|||:||..:.:|:....|....::|||:||..|....|.|: :..:..|..:.|
Zfish   571 CTDVAARGIDVRGVPYVINVTLPDEKENYVHRIGRVGRADRMGLAISLVAMEKEKVWYH 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	56/179 (31%)
		DEXDc	22..232	CDD:214692	58/185 (31%)
		HELICc	239..370	CDD:238034	43/179 (24%)
		DUF4217	411..470	CDD:290667
ddx1	NP_001184253.1	SrmB	1..>62	CDD:223587
		P-loop_NTPase	4..>70	CDD:304359
		SPRY_DDX1	93..245	CDD:293933
		DEXDc	238..439	CDD:214692	60/190 (32%)
		P-loop_NTPase	266..426	CDD:304359	55/175 (31%)
		Helicase_C	493..609	CDD:278689	27/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010