DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9630 and ddx1

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001011133.1	Gene:	ddx1 / 496549	XenbaseID:	XB-GENE-969096	Length:	740	Species:	Xenopus tropicalis

Alignment Length:	357	Identity:	101/357 - (28%)
Similarity:	149/357 - (41%)	Gaps:	83/357 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 KETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGNSIEEDIATLRRETPC 138
            |..|..||   ||:|.|:||||.|....:.||.::.|...|.:.||:||.:.:|.: ||......
Frog   281 KNLPNAPK---ALIIEPSRELAEQTLNNVKQFKKYVDSPKLRELLIIGGVAAKEQL-TLLENGVD 341

  Fly   139 ILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRTG-- 201
            |:|.||||::||...  ..||| :||:   ||||||||.||..|:...:|.|.|.:|:....|
Frog   342 IVVGTPGRIDDLIST--GKLNL-SQVR---FLVLDEADGLLSQGYSDFINRIHGQIPQVTSDGKR 400

  Fly   202 ----LFSAT-QTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEFLSS 261
                :.||| .:.:|..|....:..|..|.:|.:.||  |..:.:....|.|:         ...
Frog   401 LQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSV--PETVHHVVVPVNPK---------KDK 454

  Fly   262 PATVIGKVMV----------FFPTCACVEYWAEALPPLLPKRTVLGI------------------ 298
            ....:||..:          ..|.....|.|:||:..|..:.||..|
Frog   455 QWERLGKNHIRTDGVHDKDNTRPGGNSAEMWSEAIKVLKGEYTVRAIKEHKMDQAIIFCRTKLDC 519

  Fly   299 --------------------------HGKMK-NKRANVVEKFRNTPQAVLLCTDVLARGLDVPEI 336
                                      |...| .:|.:.:|:|:......|:||||.|||:|:..:
Frog   520 DNMEQYFIQQGGGPDKKGHQFSCVCLHSDRKPQERKHNLERFKKCEVRFLICTDVAARGIDIHGV 584

  Fly   337 EWVVQWDPPSTASSFVHRVGRTARQGNEGNAL 368
            .:|:....|....::|||:||..|....|.|:
Frog   585 PYVINVTLPDEKQNYVHRIGRVGRAERMGLAI 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	59/158 (37%)
		DEXDc	22..232	CDD:214692	61/164 (37%)
		HELICc	239..370	CDD:238034	37/185 (20%)
		DUF4217	411..470	CDD:290667
ddx1	NP_001011133.1	Interaction with dsRNA. /evidence=ECO:0000250\|UniProtKB:Q91VR5	1..448		64/178 (36%)
		DEAD-like_helicase_N	4..>64	CDD:391939
		SPRY_DDX1	93..246	CDD:293933
		DEADc_DDX1	264..430	CDD:350696	59/158 (37%)
		SrmB	284..>624	CDD:223587	100/354 (28%)
		DEAD box. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00541	370..373		2/2 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010