DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9630 and CG9253

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_610090.1	Gene:	CG9253 / 35379	FlyBaseID:	FBgn0032919	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	174/547 - (31%)
Similarity:	262/547 - (47%)	Gaps:	116/547 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 WSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQ 70
            |..|.   |::|:.|......::..:.:|..|||:.|..|||...|.||||||.||.:|:|..|.
  Fly    63 WKDLG---LNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHALL 124

  Fly    71 RRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQL------IVGGNSIEEDI 129
            .       .|:...|||::||||||.||.|   ||      |.|...:      :|||..:....
  Fly   125 E-------NPQRYFALVLTPTRELAFQIGE---QF------EALGSGIGIKCCVVVGGMDMVAQG 173

  Fly   130 ATLRRETPCILVCTPGRLED-LFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGY 193
            ..|.:: |.|::.|||||.| |...||.:|      |::::||:|||||:|::.|:..::.||..
  Fly   174 LQLAKK-PHIIIATPGRLVDHLENMKGFNL------KAIKYLVMDEADRILNMDFEVELDKILKV 231

  Fly   194 LPRQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEF 258
            |||:|||.|||||.|.:|..|.||.|::||.|.|..|  ..|..:||..|..:..:.|.|.|:..
  Fly   232 LPRERRTFLFSATMTKKVKKLQRASLKDPVKVEVSNK--YQTVEQLQQSYLFIPVKYKDVYLVHI 294

  Fly   259 LSSPATVIGKVMVFFPTCACVEYWAEALPPLLPKRTVLGIHGKM-KNKRANVVEKFRNTPQAVLL 322
            |:..|.  ...|:|..||......|..|..|  ....:.:||:| :|||...:.||:...:::|:
  Fly   295 LNELAG--NSFMIFCSTCNNTVKTALMLRAL--GLAAIPLHGQMSQNKRLAALNKFKAKNRSILI 355

  Fly   323 CTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQK 387
            .|||.:||||:|.::.||.:|.|:.:..::||||||||.|..|.|:. |:...|     :::.|:
  Fly   356 STDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAIT-LVSQYD-----IELYQR 414

  Fly   388 VE--LTKLLT----EEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECS 446
            :|  |.|.||    ||.|           |:....|:..|.:                      :
  Fly   415 IEHLLGKQLTLYKCEEDE-----------VMALQERVAEAQR----------------------T 446

  Fly   447 AILRLKDLDLGKMATAYGLLQLPRMPELKNYQGGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMET 511
            |.|.||||:    .|..|           :.:||.             |:.:::.....:|:|:.
  Fly   447 AKLELKDLE----DTRGG-----------HKRGGD-------------THDDSENFTGARKRMKP 483

  Fly   512 YEQTGSWPGQKQHKKRVESWDQTKKAK 538
            ...||. .|:|...|:  :|.:.|:.:
  Fly   484 MGGTGG-GGRKSFGKK--NWSKGKQKR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	89/226 (39%)
		DEXDc	22..232	CDD:214692	87/216 (40%)
		HELICc	239..370	CDD:238034	47/131 (36%)
		DUF4217	411..470	CDD:290667	11/58 (19%)
CG9253	NP_610090.1	SrmB	34..498	CDD:223587	171/534 (32%)
		DEADc	63..264	CDD:238167	89/226 (39%)
		HELICc	274..403	CDD:238034	47/133 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451381
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940