DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9630 and CG5800

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	669	Identity:	208/669 - (31%)
Similarity:	315/669 - (47%)	Gaps:	98/669 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RKKWSSLDKP--------PLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTL 59
            :.|::.:|..        |||....:.:....|...|.||..:|...|..|||...|:|||||||
  Fly    60 KTKYAEIDATAIKKFAQFPLSKKTQKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTL 124

  Fly    60 AFLVPMLEILQRRHKETPWGPKE-IGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGN 123
            |||:|:||.|..    ..|...: :||::||||||||.||.|.|.:..:|.|   .:..||:||.
  Fly   125 AFLIPVLEHLFM----NKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHHD---FSAGLIIGGK 182

  Fly   124 SIEEDIATLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVN 188
            :::  ....|.:...||:|||||   |.|..  |.|......::|.||||||||.||:||:.::|
  Fly   183 NLK--FERTRMDQCNILICTPGR---LLQHM--DENPLFNTSTMEMLVLDEADRCLDMGFQKTLN 240

  Fly   189 NILGYLPRQRRTGLFSATQTTEVTDLIRAGLRNPVLV-----------SVKEKASVNT-----PA 237
            :|:...|..|:|.|||||||..|.||.|..|::||.|           |...|.:.||     |.
  Fly   241 SIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPE 305

  Fly   238 RLQNFYRIVEPELKFVALLEFLSSPATVIGKVMVFFPTCACVEYWAEALPPLLPKRTVLGIHGKM 302
            .||..|.::..|.|...|..|:.:  .:..|::||..:|...:|..|....|.|...:|.::|.:
  Fly   306 LLQQSYVVLNLEDKITMLWSFIKN--HLKQKIIVFVASCKQAKYLYEIFCKLRPGSPLLALYGTL 368

  Fly   303 -KNKRANVVEKFRNTPQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGN 366
             :::|..:.|.|......|:..|||.:||||.|.:.||||.|.|...|.::||.||:||....|.
  Fly   369 HQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGE 433

  Fly   367 ALVFLLPSEDAY-VHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGM 430
            .|:.|.|||:.| :..||....::: :.:..:.:.....:.|:.|.|.|...|:|.       ..
  Fly   434 CLLVLTPSEEEYMISALKEQLNIDI-RCVQIDPKKLFSPRVKIEAFLAQFPELRAT-------AQ 490

  Fly   431 RAFVSHVRAYTKHECSAILRLKDLDLGKMATAYGLLQLPRMPELKNY------------QGGGYV 483
            |||:|::::........:..:..|||...|.:.||...||:|.|:.:            ||..
  Fly   491 RAFLSYIKSVFLMRNKRLFNVFSLDLDAFAQSLGLAVTPRVPFLEKFLWRQKQLQQQKEQGDN-- 553

  Fly   484 APAFEVDLSKLT-----------YKNAQKEQVRQKKMETYEQTGSWPGQKQHKKRVESWDQT--- 534
            |.:....|||||           .:|:..|...:.|.:.::..|. |.:...:...|:..:.
  Fly   554 AKSINPLLSKLTKQQSFGGGDEDEENSDDEDFIKVKRKDHDVEGE-PVKLDEEDDTENEAEAPLV 617

  Fly   535 --KKAKLDAK---SKKELRKAKKQRKKAA---EAEASRSGKGK-----KRQQFSQEDLDELASDI 586
              |:.||..|   :||.|:|..:...|..   |.|.....:.:     .||:...:|.|:...::
  Fly   618 VPKREKLVTKASLAKKALKKNLQVNSKLKFDDEGETMADDRSQMKALSARQRTVNQDDDDGGINL 682

  Fly   587 RLFKRLKKNKISEED-FDK 604
            .|.|.|    ::||| :||
  Fly   683 VLSKAL----LTEEDQYDK 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	94/239 (39%)
		DEXDc	22..232	CDD:214692	92/221 (42%)
		HELICc	239..370	CDD:238034	44/131 (34%)
		DUF4217	411..470	CDD:290667	14/58 (24%)
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	151/427 (35%)
		DEADc	74..277	CDD:238167	92/216 (43%)
		HELICc	311..437	CDD:238034	42/127 (33%)
		DUF4217	474..530	CDD:290667	16/62 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451436
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950