Protein Alignment CG9630 and Ddx49

DIOPT Version :10

• Sequence 1: NP_649777.1
• Gene: CG9630 / 40974
• FlyBaseID: FBgn0037561
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001020093.2
• Gene: Ddx49 / 234374
• MGIID: 2136689
• Length: 480
• Species: Mus musculus
• Alignment Length: 572
• Identity: 160/572 - (27%)
• Similarity: 256/572 - (44%)
• Gaps: 137/572 - (23%)

  Fly    14 LSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQRRHKETPW 78
            ||..:::..:..|.:|.||||...||.:|..:|....|.||||||.||::|:|:.|    .|.|:
Mouse     9 LSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKL----SEDPY 69

  Fly    79 GPKEIGALVISPTRELARQISE---VLAQFLEHEDLEHLNQQLIVGGNSIEEDIATLRRETPCIL 140
            |   |..||::||||||.||:|   ||.:.|..:|.      :||||..:......|.|: |.::
Mouse    70 G---IFCLVLTPTRELAYQIAEQFRVLGKPLGLKDC------IIVGGMDMVAQALELSRK-PHVV 124

  Fly   141 VCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLG---FKTSVNNILGYLPRQRRTGL 202
            :.|||||.| ..|..:..|:    |.::|||:|||||||:.|   |.|.:..||..:|.:|:|.|
Mouse   125 IATPGRLAD-HLRSSNTFNM----KKIQFLVMDEADRLLEQGCTDFTTDLETILAAVPARRQTLL 184

  Fly   203 FSATQTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEFLSSPATVIG 267
            ||||.|..:.:|.......|..  .:.:|:|.|..:|...|.:|..::|...|:..:.:....:.
Mouse   185 FSATLTDTLKELQGLATNEPFF--WEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLE 247

  Fly   268 --KVMVFFPTC-ACVEYWAEALPPLLPKRT--VLGIHGKMKNK-RANVVEKFRNTPQAVLLCTDV 326
              .:::|..|| .|     :.|..:|.|..  .:.:|..||.| |...:.||:::...:|:.|||
Mouse   248 DCSIIIFTNTCKTC-----QILCMMLRKFNFPTVALHSMMKQKERFAALAKFKSSIYRILIATDV 307

  Fly   327 LARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVELT 391
            .:||||:|.::.|:..:.|.....::||||||||.|.:|.|:..:...:...:|.::...|.:|.
Mouse   308 ASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLLHAIEEQIKQQLA 372

  Fly   392 KLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECSAILRLKDLDL 456
            :|:.||||        :..:|.|::                       ..:.||...|.....|
Mouse   373 ELVVEEAE--------VLQILTQVN-----------------------VVRRECEIKLEASHFD- 405

  Fly   457 GKMATAYGLLQLPRMPELKNYQGGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGSWPGQ 521
                                                       :|:::.::|....|
Mouse   406 -------------------------------------------EKKEINKRKQMILE-------- 419

  Fly   522 KQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEAEASRSGKGKKRQQ 573
                        .|...|:||.|.||.|.|:|.::..|    :.|:..:||:
Mouse   420 ------------GKDPDLEAKRKAELAKIKQQNRRFKE----KVGQTLRRQK 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc_DDX55	18..226	CDD:350718	83/213 (39%)
		SF2_C_DEAD	239..371	CDD:350174	41/137 (30%)
		DUF4217	414..470	CDD:464056	5/55 (9%)
Ddx49	NP_001020093.2	SrmB	1..380	CDD:440279	135/396 (34%)
		Q motif	2..30		7/20 (35%)
		DEAD box	152..155		2/2 (100%)
		PRK03918	<364..>447	CDD:235175	27/181 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	438..480		5/22 (23%)