DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9630 and B0511.6

DIOPT Version :9

Sequence 1:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_492779.1	Gene:	B0511.6 / 172954	WormBaseID:	WBGene00015232	Length:	544	Species:	Caenorhabditis elegans

Alignment Length:	531	Identity:	188/531 - (35%)
Similarity:	279/531 - (52%)	Gaps:	76/531 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQ----RRHKETPW 78
            :|:.||..||..||.:|..:|..||..|||.|.|.||||||||||:|.:|:|.    ::|..|
Worm    79 LLKAVQGLGFTTMTEIQAKSIDPLLEGKDVLASAKTGSGKTLAFLLPAIELLHKLNWKQHNGT-- 141

  Fly    79 GPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGN--SIEEDIATLRRETPCILV 141
                 |.:::||||||:.|...||::.||..:|.:   .|::||:  |.|:|...   :...|||
Worm   142 -----GVIIVSPTRELSMQTYGVLSELLEGSNLTY---GLVMGGSNRSAEKDKLA---KGVSILV 195

  Fly   142 CTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRTGLFSAT 206
            .|||||.|..|...:.|     |::::.|::|||||:||:||:..:..:|.:||:||::.|||||
Worm   196 ATPGRLLDHLQNTDNFL-----VRNMKCLIIDEADRILDIGFEIEMQQVLRHLPKQRQSMLFSAT 255

  Fly   207 QTTEVTDLIRAGLR-NPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEFLSSPATVIGKVM 270
            .:.:|.:|::..|. |||.|||.|||...|...||..|.:...:.:.:.|..||....|  .|||
Worm   256 HSPKVDELVKLALHSNPVRVSVHEKAEEATVEGLQQGYIVAPSDKRLLLLFTFLKKNKT--KKVM 318

  Fly   271 VFFPTCACVEYWAEALPPL-LPKRTVLGIHGKMK-NKRANVVEKFRNTPQAVLLCTDVLARGLDV 333
            |||.:|..|::..|.|..: :|   .:.||||.| .||.....:|......:||||||.|||||:
Worm   319 VFFSSCNSVKFHHELLNYIDIP---CMSIHGKQKQQKRTTTFFQFCQAETGILLCTDVAARGLDI 380

  Fly   334 PEIEWVVQWDPPSTASSFVHRVGRTARQGN-EGNALVFLLPSEDAYVHFLKINQKVELTKLLTEE 397
            |.::|:||:||......::||||||||..| .|.||:.|.|.|..::.:||. .||.|.:.
Worm   381 PAVDWIVQYDPTDEPREYIHRVGRTARGTNGSGKALLVLRPEELGFLRYLKA-AKVTLNEF---- 440

  Fly   398 AEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECSAILRLKDLDLGKMATA 462
                :....|:..:..||..|.:.:..:......|:..::|||..|....|..:.::||..::.:
Worm   441 ----EFSWSKVANIQSQLENLISKNYYLNKSAKEAYKCYLRAYDSHSLKDIFDVTNMDLTAVSKS 501

  Fly   463 YGLLQLPRMPELKNYQGGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGSWPGQKQHKKR 527
            :                 |:..|.| ||   |...|..|.::|.|.        |..|   ::|:
Worm   502 F-----------------GFSVPPF-VD---LPISNKPKVEIRSKL--------SGAG---YRKK 534

  Fly   528 VESWDQTKKAK 538
            .:|:  |.|||
Worm   535 KQSF--TFKAK 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	88/214 (41%)
		DEXDc	22..232	CDD:214692	92/216 (43%)
		HELICc	239..370	CDD:238034	55/133 (41%)
		DUF4217	411..470	CDD:290667	11/58 (19%)
B0511.6	NP_492779.1	DEADc	68..276	CDD:238167	88/214 (41%)
		DEXDc	83..291	CDD:214692	95/225 (42%)
		Helicase_C	312..407	CDD:278689	43/99 (43%)
		DUF4217	450..508	CDD:290667	12/74 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920