Protein Alignment Mcm2 and PRL

DIOPT Version :9

• Sequence 1: NP_477121.1
• Gene: Mcm2 / 40973
• FlyBaseID: FBgn0014861
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_001190655.1
• Gene: PRL / 828153
• AraportID: AT4G02060
• Length: 716
• Species: Arabidopsis thaliana
• Alignment Length: 704
• Identity: 241/704 - (34%)
• Similarity: 355/704 - (50%)
• Gaps: 110/704 - (15%)

  Fly   185 QSFLRTFVDERGAYTYRDRIRRMCEQNMSSFVVSYTDLANKEHVLAYF---LPEAPFQMLEIFDK 246
            :.||..|.|..|...|.:.::.:..:.:.:..|...||.|.:.....|   |.|...:.:.||..
plant    14 KGFLENFADANGRSKYMEILQEVSNRKIRAIQVDLDDLFNYKDESEEFLGRLTENTRRYVSIFSA 78

  Fly   247 VAKDMV---LSIFP---------------TYERVTTEIHVRI-SELPLIEE-------------L 279
            ...:::   ...||               |.....::.|.:| ||:....|             :
plant    79 AVDELLPEPTEAFPDDDHDILMTQRADDGTDNPDVSDPHQQIPSEIKRYYEVYFKAPSKGRPSTI 143

  Fly   280 RTFRKLHLNQLVRTLGVVTATTGVLPQLSVIKYDCVKCGYVLGPFVQSQNTEIKPGSCP--ECQ- 341
            |..:..|:.||||..|:||..:.|.|.::|..|.|..||:.:...|.|: ..:....||  .|:
plant   144 REVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSR-VFMPLFKCPSSRCRL 207

  Fly   342 --STGPFSINMEQTLYRNYQKITLQESPGRIPAGRIPRSKDVILLADLCDQCKPGDELEVTGI-- 402
              ..|...:.:..:.:..:|:..:||....:|.|.||||..|.|..:|..:..|||.:|.:||
plant   208 NSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFL 272

  Fly   403 ---YTNNYDGSLNTDQGFPVFATVIIAN---------HVVVKDSKQVVQSLTDEDIATIQKLSKD 455
               ||           ||......::|:         |...|..:...|...:|.||   :|::|
plant   273 PIPYT-----------GFKALRAGLVADTYLEATSVTHFKKKYEEYEFQKDEEEQIA---RLAED 323

  Fly   456 PRIVERVVASMAPSIYGHDYIKRALALALFGGESKNPGEKHKVRGDINLLICGDPGTAKSQFLKY 520
            ..|..::..|:||.||||:.||:||.|.|.|...:...:..|:|||:::.:.||||.||||.||:
plant   324 GDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKH 388

  Fly   521 TEKVAPRAVFTTGQGASAVGLTAYVRRNPVSREWTLEAGALVLADQGVCLIDEFDKMNDQDRTSI 585
            ...||||.|:|||:|:|.|||||.|.|:.|:.|..||.|||||||.|:|.|||||||::.|||:|
plant   389 IINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAI 453

  Fly   586 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSMTFSENVNLSEPILSRFDVLCVVKD 650
            ||.||||::||:||||.|||.||..|:|||||..||||...|.:||:||...:|||||:|.::.|
plant   454 HEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILD 518

  Fly   651 EFDPMQDQQLAKFVVHSHMKHHPSEEEQPELE-EPQLKTVDEIPQDLLRQYIVYAKENIRPKLTN 714
            ..|...|.:|||.|:|.|     ..||.|.|. ||       :..::||.||..|: .:.|.:..
plant   519 RADMDSDLELAKHVLHVH-----QTEESPALGFEP-------LEPNILRAYISAAR-RLSPYVPA 570

  Fly   715 IDEDKIAKMYAQLRQESFATGSLP---ITVRHIESVIRMSEAHARMHLRENVMEADVSMAIRMML 776
            ..|:.||..|:.:|||. |..:.|   .|||.:.|::|:|.|.||:...|:|.::||..|:|:|.
plant   571 ELEEYIATAYSSIRQEE-AKSNTPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQ 634

  Fly   777 ESFI-----EAQK---------FSVM-------KKMRSTFQKYLSF--QKDHSE 807
            .|.|     :.||         :|::       ||...::...|::  :|.:||
plant   635 MSKISLYADDRQKAGLDAISDTYSIIRDEAARSKKTHVSYANALNWISRKGYSE 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm2	NP_477121.1	MCM2_N	59..166	CDD:372227
		MCM_N	184..270	CDD:379644	19/105 (18%)
		MCM	276..780	CDD:214631	209/539 (39%)
PRL	NP_001190655.1	MCM_N	16..98	CDD:405270	17/81 (21%)
		MCM	139..638	CDD:214631	208/527 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266497at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820