Protein Alignment Mcm2 and mcm7

DIOPT Version :10

• Sequence 1: NP_477121.1
• Gene: Mcm2 / 40973
• FlyBaseID: FBgn0014861
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_998877.1
• Gene: mcm7 / 407945
• XenbaseID: XB-GENE-5946446
• Length: 720
• Species: Xenopus tropicalis
• Alignment Length: 723
• Identity: 232/723 - (32%)
• Similarity: 369/723 - (51%)
• Gaps: 111/723 - (15%)

  Fly   185 QSFLRTFV--DERGA--YTYRDRIRRMCEQNMSSFVVSYTDLANKEHVLAYFLPEAPFQMLEIFD 245
            ::||:.|.  ||.|.  :.|..::..:..:...:..:...|||.::..|...:.|...:...:|
 Frog    13 KTFLQEFYKDDELGKKNFKYGVQLANIAHREQVALYIDLDDLAEEDPELVDAICENTRRYTNLF- 76

  Fly   246 KVAKDMVLSIFPTYER---------------------------VTTEIH-------VRISEL--- 273
               .|.|..:.|.|:.                           .|.:.|       :|..||
 Frog    77 ---ADAVQELLPQYKEREVVHKDALDVYIEHRLMMEQRGRDPSETRDPHNQYPPELMRRFELYFK 138

  Fly   274 -PLIEELRTFRKL---HLNQLVRTLGVVTATTGVLPQLSVIKYDCVKCGYVLGPFVQSQNTEIKP 334
             |...:.|..|.:   .:.:||...|:||..|.|.|.:.|..|.|.:||......:||. |.:..
 Frog   139 APSSSKARVVRDVKADSIGKLVTVRGIVTRVTEVKPMMVVATYTCDQCGAETYQPIQSP-TFMPL 202

  Fly   335 GSCP--ECQ---STGPFSINMEQTLYRNYQKITLQESPGRIPAGRIPRSKDVILLADLCDQCKPG 394
            ..||  |||   |.|...:....:.:..:|::.:||...::|.|.|||...|.:..:.....:||
 Frog   203 IMCPSRECQTNRSGGRLYLQTRGSKFIKFQELKIQEHSDQVPVGNIPRCMSVYVRGENTRLAQPG 267

  Fly   395 DELEVTGIYTNNY-DGSLNTDQGFPVFATVIIANHVVVK-----DSKQVVQSLTDEDIATIQKLS 453
            |.:.:||::.... .|.....||  :.:...:.:|.:||     |.:...:.|::|::..|
 Frog   268 DHVSITGVFLPMLRTGFRQVVQG--LLSETYLESHRLVKMNKTEDDELGTEELSEEELRQI---- 326

  Fly   454 KDPRIVERVVASMAPSIYGHDYIKRALALALFGGESKNPGEKHKVRGDINLLICGDPGTAKSQFL 518
            .:....|::.||:||.||||:.:|:||.|.|.||...:| ...|:||:||:.:.||||.||||.|
 Frog   327 TEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDNSP-RGMKIRGNINICLMGDPGVAKSQLL 390

  Fly   519 KYTEKVAPRAVFTTGQGASAVGLTAYVRRNPVSREWTLEAGALVLADQGVCLIDEFDKMNDQDRT 583
            .|.:::|||:.:|||:|:|.|||||.|.::||:.|.|||.|||||||||||.|||||||.|.|||
 Frog   391 SYIDRLAPRSQYTTGRGSSGVGLTAAVMKDPVTGEMTLEGGALVLADQGVCCIDEFDKMMDTDRT 455

  Fly   584 SIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSMTFSENVNLSEPILSRFDVLCVV 648
            :|||.||||:|||:||||:|:|.|||:::|||||..|||:|..|..:|:.|...:|||||:|.::
 Frog   456 AIHEVMEQQTISIAKAGIMTTLNARCSILAAANPAYGRYNPKKTVEQNIQLPAALLSRFDLLWLI 520

  Fly   649 KDEFDPMQDQQLAKFV--VHSHMKHHPSEEEQPELEEPQLKTVDEIPQDLLRQYIVYAKENIRPK 711
            :|:.|...|.:||:.:  ||.|.|..||:.:..:::             |:|:||...|.. :|.
 Frog   521 QDKPDRDNDLRLAQHITYVHQHSKQPPSQFQPLDMK-------------LMRRYITMCKRK-QPA 571

  Fly   712 LTNIDEDKIAKMYAQLRQESFATGSLPIT-VRHIESVIRMSEAHARMHLRENVMEADVSMAIRMM 775
            :.....|.:...|.::|:|:.....:..| .|.:.|::|:|.|.||:.|.:.|.:.||:.|:|:
 Frog   572 IPESLADYLTAAYVEMRKEARTNKDMTFTSARTLLSILRLSTALARLRLEDVVEKEDVNEAMRL- 635

  Fly   776 LESFIEAQKFSVM--KKMRSTFQKYLSFQKDHSELLFFILRQLTLDQLAYIRCKDGPGATHVEIM 838
                .|..|.|::  |...|..|:       .::::|..:|::..::          ||..|:..
 Frog   636 ----TEMSKDSLLGDKGQTSRTQR-------PADVIFSTIREMVPEK----------GARSVKYS 679

  Fly   839 ERDLIERA 846
            |.:  :||
 Frog   680 EAE--QRA 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm2	NP_477121.1	MCM2_N	59..166	CDD:403724
		MCM_N	182..271	CDD:464206	20/123 (16%)
		MCM	276..780	CDD:214631	195/520 (38%)
mcm7	NP_998877.1	MCM_N	9..102	CDD:464206	17/92 (18%)
		MCM	144..640	CDD:214631	196/522 (38%)
		Arginine finger	512..515		2/2 (100%)