Protein Alignment Mcm2 and LOC3290529

DIOPT Version :10

• Sequence 1: NP_477121.1
• Gene: Mcm2 / 40973
• FlyBaseID: FBgn0014861
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_061502321.1
• Gene: LOC3290529 / 3290529
• VectorBaseID: AGAMI1_014641
• Length: 1119
• Species: Anopheles gambiae
• Alignment Length: 715
• Identity: 211/715 - (29%)
• Similarity: 323/715 - (45%)
• Gaps: 130/715 - (18%)

  Fly   220 TDLANK----EHV-----LAYFLPEAPFQMLEIFD--------------KVAKDMV---LSIFPT 258
            |||.|.    :||     |.....|.|.....||.              :..|.::   |.:.|.
Mosquito    14 TDLLNNSDDLQHVSIHVNLTQLQREQPQLFARIFQDTQTELARWNECLLRAQKSLIEGNLFLDPG 78

  Fly   259 YERVTTEIHVRISELPLI-EELRTFRKLHLNQLVRTLGVVTATTGVLPQLSVIK-------YDCV 315
            :: |....|||...:|:. .|||  :..:.|.  .::|......|.:.::|..:       |.|.
Mosquito    79 FQ-VKENCHVRFVNVPVSPAELR--KSAYPNN--DSVGQFLQVKGSVIRMSSSRFLEYRREYACT 138

  Fly   316 KC------------GYVLGPFVQSQNTEIKPGSCPECQSTG------PFSINMEQTLYRNYQKIT 362
            :|            .||..|          ||.||..:..|      |.|...:..|.|:||:|.
Mosquito   139 RCKQKVVIEAEYCKSYVFEP----------PGPCPNAREAGCRGQLQPVSAQPQPELCRDYQEIR 193

  Fly   363 LQE--SPGRIPAGRIPRSKDVILLADLCDQCKPGDELEVTGIYTNNYDGSLNTDQGFPVFATVII 425
            :||  |...:||..:     |.|..||.|.|:|||.:.|.|...:.:.   ....|.....|:.:
Mosquito   194 IQEIMSERNVPASLV-----VTLEDDLVDSCQPGDCVTVCGPIEHRWK---PPTVGRRTEVTIAM 250

  Fly   426 -ANHVVVKDSKQ-----------VVQSLTDEDIATIQKLSKDPRIVERVVASMAPSIYGHDYIKR 478
             ||.|..::||.           .|.:...|.:..|.:|:....:|:    |:||:|.|...:|.
Mosquito   251 RANSVAREESKASWAKDLPEHLLCVPAEWQEVLREIGELAARDLLVQ----SIAPAIRGMYPVKL 311

  Fly   479 ALALALFG-GESKNPGEKH-KVRGDINLLICGDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGL 541
            |:||||.. .|....||:. .|||..:||:.||||.||||.|||..::|.|||:|||.|.|:.||
Mosquito   312 AIALALASCTERVGDGEQQATVRGHSHLLLVGDPGLAKSQLLKYASEIASRAVYTTGMGCSSAGL 376

  Fly   542 TAYVRRNPVSREWTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQ 606
            ||...::  ..||.||||||||||.|:|.||||:.|.:.|:.|||||||||:||::|||:|..|.
Mosquito   377 TAAAVKD--EGEWQLEAGALVLADGGICCIDEFNLMRETDKASIHEAMEQQTISVAKAGMVCKLS 439

  Fly   607 ARCTVIAAANP--IGGRYDPSMTFSENVNLSEPILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHM 669
            .||.|:||.||  :....|.....:||:.:..|:|||||::.::||......|..:|     :|:
Mosquito   440 TRCVVLAATNPKNLYTMSDGLGKSAENIGIGGPLLSRFDMVMILKDVRAADWDADIA-----NHL 499

  Fly   670 KHHPSEEEQPELEEPQLKTVDEIPQDLLRQYIVY--AKENIRPKLTNIDEDKIAKMYAQLRQESF 732
            ......:|:.|..|.:....|.:....|.:..::  |.::..|:::......:...|...|.:.:
Mosquito   500 LAQALLDEERECFEGEGNRTDRVAHWELEKLQLHFAAIKDFHPRVSPEANVILGAYYKACRSDPY 564

  Fly   733 ATGSLPITVRHIESVIRMSEAHARMHLRENVMEADVSMAIRMMLESF----IEAQKFSVMKKM-- 791
            ...: ..|||.::|:.|:::||||:.||..|...|....|::|..|:    |....:.::|..
Mosquito   565 RDPT-RTTVRLLDSLFRLAQAHARLLLRNEVTPIDAITIIQLMEASWGFGKIGIPTYDLIKAQLP 628

  Fly   792 ----RSTFQKYLSFQKDHSELLFFILRQLTLDQLAYIRCKDGPGATHVEIMERDLIERAKQLDIV 852
                :.|..:.|.....|.          .:...|.:|..| |..  :....|:|||:.|:..::
Mosquito   629 LGPEQGTIDRLLDVLNLHG----------VVQDTATVRPID-PNI--LRRYHRELIEKQKRKQLI 680

  Fly   853  852
            Mosquito   681  680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm2	NP_477121.1	MCM2_N	59..166	CDD:403724
		MCM_N	182..271	CDD:464206	18/76 (24%)
		MCM	276..780	CDD:214631	178/553 (32%)
LOC3290529	XP_061502321.1	None