Protein Alignment Mcm2 and Mcm6

DIOPT Version :9

• Sequence 1: NP_477121.1
• Gene: Mcm2 / 40973
• FlyBaseID: FBgn0014861
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_058983.1
• Gene: Mcm6 / 29685
• RGDID: 61967
• Length: 821
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 217/670 - (32%)
• Similarity: 352/670 - (52%)
• Gaps: 91/670 - (13%)

  Fly   177 RTEIANR----FQSFLRTFVDERGAYTYRDRIRRMCEQNMSSFVVSYTDLANKEHVLAYFLPEAP 237
            |.|:|.:    |..||..|....|...|......:.....::.|||:.||......|:..:.|..
  Rat    19 RDEVAEKCQKLFLDFLEEFQGSDGEIKYLQFAEELIRPERNTLVVSFADLEQFNQQLSTTIQEEF 83

  Fly   238 FQM-------LEIFDKVAKDMVLSIFPTYERVTTEIHVRISELPLIEELRTFRKLHLNQLVRTLG 295
            :::       |:.|.|..|::..:         .:.:|...:||...::|......:..|.|..|
  Rat    84 YRVYPYLCRALKTFVKDRKEIPFA---------KDFYVAFQDLPTRHKIRELTSSRIGLLTRISG 139

  Fly   296 VVTATTGVLPQLSVIKYDCVKCGYVLGPFVQSQNTEIKPGSC--PECQSTGPFSINMEQTLYRNY 358
            .|..|..|.|:|....:.|:.|..|:.. |:.|....:|..|  |.|.:...|.::..::.:.::
  Rat   140 QVVRTHPVHPELVSGTFLCLDCQTVIKD-VEQQFKYTQPSICRNPVCANRKRFLLDTNKSRFVDF 203

  Fly   359 QKITLQESPGRIPAGRIPRSKDVILLADLCDQCKPGDELEVTGIY-----------------TNN 406
            ||:.:||:...:|.|.||||.:|:|.|:..:..:.||..:.||..                 ||:
  Rat   204 QKVRIQETQAELPRGSIPRSLEVVLRAEAVESAQAGDRCDFTGTLIVVPDVSKLSTPGARAETNS 268

  Fly   407 YDGSLNTDQGFPV---------------FATVIIANHVV----------VKDSKQVVQS----LT 442
               .::...|:..               :..|.:|.:|.          ::|.:|..:|    :|
  Rat   269 ---RVSGADGYETEGIRGLRALGVRDLSYRLVFLACYVAPTNPRFGGKELRDEEQTAESIKNQMT 330

  Fly   443 DEDIATIQKLSKDPRIVERVVASMAPSIYGHDYIKRALALALFGGESKNPGEKHKVRGDINLLIC 507
            .::...:.::|:|..:...:..|:.|:|:|:|.:||.:.|.||||..|..||...:|||||:.|.
  Rat   331 VKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIV 395

  Fly   508 GDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGLTAYVRRNPVSREWTLEAGALVLADQGVCLID 572
            |||.||||||||:.::.:||||:|:|:.:||.||||.|.|:..|.|:.:|||||:|||.|||.||
  Rat   396 GDPSTAKSQFLKHVDEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCID 460

  Fly   573 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSMTFSENVNLSEP 637
            |||||:.:|:.:||||||||:|||:|||:..:|.||.:::|||||:.|.||.|.:..:|:|||.|
  Rat   461 EFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAP 525

  Fly   638 ILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHMKHHPSEEEQPELEEPQLKTVDEI-PQDLLRQYI 701
            |:||||:..::.||.:.:.|..:|:.:|..|.:          :||    ::|.: ..|.:|:|:
  Rat   526 IMSRFDLFFILVDECNEVTDYAIARRIVDLHSR----------IEE----SIDRVYSLDDIRRYL 576

  Fly   702 VYAKENIRPKLTNIDEDKIAKMYAQLRQ---ESFATGSLPITVRHIESVIRMSEAHARMHLRENV 763
            ::|:: .:||::...||.|.:.|.:|||   ......|..||||.:||:||:||:.||||..:.|
  Rat   577 LFARQ-FKPKISKESEDFIVEQYKRLRQRDGSGITKSSWRITVRQLESMIRLSESMARMHCCDEV 640

  Fly   764 MEADVSMAIRMMLESFIEAQ 783
            ....|..|.|::.:|.|..:
  Rat   641 QPKHVKEAFRLLNKSIIRVE 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm2	NP_477121.1	MCM2_N	59..166	CDD:372227
		MCM_N	184..270	CDD:379644	18/92 (20%)
		MCM	276..780	CDD:214631	193/555 (35%)
Mcm6	NP_058983.1	MCM_N	27..114	CDD:405270	18/95 (19%)
		MCM	119..657	CDD:214631	193/556 (35%)
		MCM6_C	711..817	CDD:408078

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820