Protein Alignment Mcm2 and mcm3

DIOPT Version :9

• Sequence 1: NP_477121.1
• Gene: Mcm2 / 40973
• FlyBaseID: FBgn0014861
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_997732.2
• Gene: mcm3 / 192323
• ZFINID: ZDB-GENE-020419-4
• Length: 807
• Species: Danio rerio
• Alignment Length: 685
• Identity: 227/685 - (33%)
• Similarity: 362/685 - (52%)
• Gaps: 70/685 - (10%)

  Fly   179 EIANRFQSFLRTFVDERGAYTYRDRIRRMCEQNMSSFVVSYTDLANKEHVLAYFLPEAPFQMLEI 243
            |:....:.:|....|::....|:.::|:|..:|.|..:|:..||..:....|..|....|:.|..
Zfish    10 EMREAQRDYLDFLDDDQDQGIYQSKVRQMISENKSRLIVNLNDLRRRNEKRAAKLLNNAFEELLA 74

  Fly   244 FDKVAKDMVLSIFPTYERVTTEIHVRISELPLIEELRTFRKLHLNQLV---RTLGVVTATTGVLP 305
            |.:..||:|.||..||.:...|..:.:.        .:|...|::...   |.||.:....|::.
Zfish    75 FQRALKDLVASIDATYAKQCEEFFIGLE--------GSFGSKHVSPRTLTSRLLGSMVCLEGIVT 131

  Fly   306 QLSVIKYDCVKCGY---VLGPFVQSQNTEIK-----PGSC---PECQSTGPFSINMEQTLYRNYQ 359
            :.|:::...|:..:   .....::.:.|::.     |.|.   .:.:...|.......::|:::|
Zfish   132 KCSLVRPKVVRSVHYCPATKKTMERKYTDLTSLDAFPSSAIYPTKDEENNPLETEFGLSVYKDHQ 196

  Fly   360 KITLQESPGRIPAGRIPRSKDVILLADLCDQCKPGDELEVTGIYTNNYDGSLNTDQGFP--VFAT 422
            .||:||.|.:.|||::|||.|:||..||.|..||||..:|.|.| ....|...   ||.  .|.|
Zfish   197 TITIQEMPEKAPAGQLPRSVDIILDNDLVDAVKPGDRTQVIGTY-RCLPGKKG---GFTSGTFRT 257

  Fly   423 VIIANHVVVKDSKQVVQSLTDEDIATIQKL--SKDPRIVERVVASMAPSIYGHDYIKRALALALF 485
            ::||.| |.:.||::....:.:|:|.|:..  |:...:.:::..|:||||:||:|||:|:...|.
Zfish   258 IMIACH-VKQMSKEISHYFSADDVAKIKSFCRSRSKNVFDQLARSLAPSIHGHEYIKKAILCMLL 321

  Fly   486 GGESKNPGEKHKVRGDINLLICGDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGLTAYVRRNPV 550
            ||..|......::|||||:|:.|||..||||.|:|....||||:.|||:|:|.|||||.|..:..
Zfish   322 GGVEKVLENGSRIRGDINVLLIGDPSVAKSQLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQE 386

  Fly   551 SREWTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAA 615
            :.|..|||||:||.|:||..|||||||:|.|||:|||.|||..::|:||||...|.|||:|:|||
Zfish   387 TGERRLEAGAMVLGDRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAA 451

  Fly   616 NPIGGRYDPSMTFSENVNLSEPILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHMKHHPSEE---- 676
            ||:.||||...|..||:.|.:.:|||||:|.::.|:.||.||::::..|:..|....|.|:
Zfish   452 NPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRDPHEQDGTA 516

  Fly   677 ------------EQPEL---EEPQLKTVDE---------------IPQDLLRQYIVYAKENIRPK 711
                        |.|:.   ||.:|:..::               :.:..:|:||..||. |.|.
Zfish   517 LALGGTIDALATEDPDATQEEEEELQVYEKHNPLLHGSKKNKDRVVSKAFMRKYIHVAKA-ISPV 580

  Fly   712 LTNIDEDKIAKMYAQLR-QESFATG---SLPITVRHIESVIRMSEAHARMHLRENVMEADVSMAI 772
            ||....:.||:.|::|| ||...:.   :.|:|.|.:|::||:|.|||:..:.:.|...|..:|:
Zfish   581 LTQDAANHIAEEYSRLRNQEQLGSDIARTSPVTARTLETLIRLSTAHAKARMSKAVELVDTEVAV 645

  Fly   773 RMMLESFIEAQKFSVMKKMRSTFQKYLSFQKDHSE 807
            .::..::.:.......|:.|:..|...|..::..|
Zfish   646 ELVQFAYFKKVLEKERKRSRNGQQDAASEDEEEEE 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm2	NP_477121.1	MCM2_N	59..166	CDD:372227
		MCM_N	184..270	CDD:379644	23/85 (27%)
		MCM	276..780	CDD:214631	198/559 (35%)
mcm3	NP_997732.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820