Protein Alignment Mcm2 and LOC1273388

DIOPT Version :10

• Sequence 1: NP_477121.1
• Gene: Mcm2 / 40973
• FlyBaseID: FBgn0014861
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_312356.3
• Gene: LOC1273388 / 1273388
• VectorBaseID: AGAMI1_009590
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 604
• Identity: 183/604 - (30%)
• Similarity: 304/604 - (50%)
• Gaps: 105/604 - (17%)

  Fly   291 VRTLGVVTATTGVLPQLSVIK-------YDCVKCGYVLGPFVQSQNTEIK------PGSCPE-CQ 341
            |.::|.:.:..|.:.:....:       :.|.:||       ..|..:.|      |.||.. |:
Mosquito   221 VSSMGKLVSVRGTIIRAGATQIMNTWCAFRCAQCG-------SEQAVQQKDGIYTTPTSCHSGCK 278

  Fly   342 STGPFSINMEQTLYRN---YQKITLQESP--GRIPAGRIPRSKDVILLADLCDQCKPGDELEVTG 401
            :...| :.::|:.:..   ||.:.|||:.  .|..||...::.::.|..:|.|...|||::.|||
Mosquito   279 ARSHF-VLLQQSAFTRMEAYQTLRLQETTQGSRTVAGSAAKNIEIELTHELVDSVCPGDDVTVTG 342

  Fly   402 IY-TNNYDGSLNTDQGFPVFATVIIANHVVVKDSKQVVQS------LTDEDIATIQKLSKDPRIV 459
            |. ..:.|||....:. .:|...:.|  |.|:.:|.|:.:      .|:.|:..|:.:..:|...
Mosquito   343 ILKARSQDGSDGAGKA-SMFKAYLQA--VYVRSNKNVLANWNRLAEFTELDMEAIRLIKAEPSPF 404

  Fly   460 ERVVASMAPSIYGHDYIKRALALALFGGESKNPGEKHKVRGDINLLICGDPGTAKSQFLKYTEKV 524
            ..:|.|:.|:||||:.:|..|.|.||||.:...    :.|.:|::|:.||||..|||.|:....|
Mosquito   405 RLLVQSLCPTIYGHEIVKAGLLLGLFGGMANTA----RTRAEIHVLVVGDPGIGKSQILQSCANV 465

  Fly   525 APRAVFTTGQGASAVGLTAYVR-RNPVSREWTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEA 588
            :||.:|..|..:|.||||..|| ...|..  :||||||||||||||.|||||||:  ..:.:.|.
Mosquito   466 SPRGIFVCGTNSSNVGLTVTVRTEKGVGA--SLEAGALVLADQGVCCIDEFDKMS--GHSGLLEV 526

  Fly   589 MEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSMTFSENVNLSEPILSRFDVLCVVKDEFD 653
            |||:|:|::|||::.::.||.||:|||||.||.|:.:.|.|||:.|...:|||||::.::.|..:
Mosquito   527 MEQRSVSVAKAGVICTVPARTTVLAAANPAGGHYNKAKTVSENLKLHPALLSRFDLVFILLDRSN 591

  Fly   654 PMQDQQLAKFV--VH-------SHMKHHPS-------------EEEQPELEEPQLK-----TVDE 691
            ...|..|...:  ||       ||::..||             ||.:|.||| :|:     .:|.
Mosquito   592 ERTDNLLTAHIQKVHGLAKAGSSHLQPQPSHPFFDASGHCSYEEEGEPPLEE-RLRLAPGEQMDL 655

  Fly   692 IPQDLLRQYIVYAKENIRPKLTNIDEDKIAKMYAQLRQESFATGSLPITVRHIESVIRMSEAHAR 756
            :|.:::::||.||::|::||||....:::.:.:.:||:.......:|:|.|.:|.:||:::|.|:
Mosquito   656 LPPEIVQKYIGYARKNVQPKLTAKAAEELREFFVELRRAHNHMDMIPVTTRQLEGLIRLTQARAK 720

  Fly   757 MHLRENVMEADVSMAIRMMLESFIEAQKFSVMKKMRSTFQKYLSFQKDHSELLFFILRQLTLDQL 821
            :.|......|.|...:.::.:|.::.                  |..|..:|.|
Mosquito   721 IDLSPEATVAHVRDVLAILRQSMLDV------------------FSTDEGDLQF----------- 756

  Fly   822 AYIRCKDGPGATHVEIMER 840
              .|..:|.|.:...::.:
Mosquito   757 --TRLTNGSGTSKTSMVRK 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm2	NP_477121.1	MCM2_N	59..166	CDD:403724
		MCM_N	182..271	CDD:464206
		MCM	276..780	CDD:214631	176/542 (32%)
LOC1273388	XP_312356.3	Mcm2	224..832	CDD:440854	182/601 (30%)