DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpA-70 and Meiob

DIOPT Version :9

Sequence 1:	NP_524274.1	Gene:	RpA-70 / 40972	FlyBaseID:	FBgn0010173	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001108505.1	Gene:	Meiob / 685099	RGDID:	1583204	Length:	470	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	81/407 - (19%)
Similarity:	160/407 - (39%)	Gaps:	57/407 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 ISSLSPYQNKWVIKARVTSKSGIRTW---SNARGEGKLFSMDLMDESGE-IRATAFKEQCDKFYD 229
            :|.|.|......|...|..|:.::.:   .|...|...||..:.|.... :..:::..:     |
  Rat    13 LSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPNHFVNVSSWGSE-----D 72

  Fly   230 LIQ-VDSVYYISKC--------QLKPANKQ--YS-SLNNAYEMTFS-GETVVQLCEDTDDD---- 277
            .|: :...:.:.:|        |.|...::  :| :..:.|::..| ..::|::|...:.|
  Rat    73 YIRSLSDNFKVGECVIIENPLIQRKETEREERFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLL 137

  Fly   278 -----PIPEIK--YNLVPISDVSGMENKAAVDTIGICKEVGELQSFVARTTNKEFKKRDITLVDM 335
                 |:.|.:  |:|..|.......:...::.:...:.|||.:.|.. :..::.::.::.|.|.
  Rat   138 SLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTT-SDRRKGQRCEVKLFDE 201

  Fly   336 SNSAISLTLWGDDAVNFDGH---VQPVILVKGTRI--NEFNGGKSLSLGGGSIMKINPDIPEAHK 395
            :..:.::|.|.::::.....   .:.||.....||  |:|....:.::...:|:.:|||.|||:.
  Rat   202 TEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANI 266

  Fly   396 LRGWFDNGGGDSVAN--------MVSARTGGGSFSTEWMTLKDARARNLGSGDKPDYFQCKAVVH 452
            |..:.......|:|:        .|:..|....::.|  .||.....|.|..| |.|....|.:.
  Rat   267 LLNFIRENKETSIADEIDSYLKESVNLNTIVNVYTVE--QLKGKALENEGKVD-PFYGILYAYIS 328

  Fly   453 IVKQENAFYRA----CPQSDCNKKVVDEGNDQFRCEKCNALFPNFKYRLLINMSIGDWTSN-RWV 512
            .:..::...:.    |  |.|...|.|..|....|.|.::...:|.....:.:.:.|.|.. |..
  Rat   329 TLNIDDETTKVVRNRC--SSCGYIVNDASNTCTICSKDSSRSRSFCLSFDVLVDLTDHTGTLRSC 391

  Fly   513 SSFNEVGEQLLGHTSQE 529
            |....|.|:.||.|..|
  Rat   392 SLSGSVAEETLGCTINE 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpA-70	NP_524274.1	rpa1	3..595	CDD:273177	81/407 (20%)
		Rep-A_N	6..107	CDD:281980
		RPA1_DBD_A	168..270	CDD:239920	20/117 (17%)
		RPA1_DBD_B	301..401	CDD:239921	22/104 (21%)
		Rep_fac-A_C	444..589	CDD:285809	21/91 (23%)
Meiob	NP_001108505.1	rpa1	<165..408	CDD:273177	53/248 (21%)
Meiob	NP_001108505.1	RPA1_DBD_B	167..270	CDD:239921	22/103 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810