Protein Alignment RPA1 and Rpa1

DIOPT Version :10

• Sequence 1: NP_524274.1
• Gene: RPA1 / 40972
• FlyBaseID: FBgn0010173
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_006534114.1
• Gene: Rpa1 / 68275
• MGIID: 1915525
• Length: 652
• Species: Mus musculus
• Alignment Length: 660
• Identity: 266/660 - (40%)
• Similarity: 387/660 - (58%)
• Gaps: 76/660 - (11%)

  Fly     2 VLASLSTGVIARIMHGEVVD-APVLQILAIKKINSAADSERYRILISDGKYFNSYAMLASQLNVM 65
            ::..||.|.|..::..|... .|:||::.|:.|::...|.|||:|:|||....|..|||:|||.:
Mouse     1 MVGHLSEGAIEVMIQQENTSIKPILQVINIRPISTGNRSPRYRLLMSDGLNTLSSFMLATQLNTL 65

  Fly    66 QHNGELEEFTIVQLDKYVTSLVGKDGAGK---------------------------RVLIISELT 103
            ...|:|....:.|:.|::.:.: |||..:                           :|:::.:|.
Mouse    66 VEGGQLASNCVCQVHKFIVNTL-KDGRMQPKPHGNPYGEQSVLRKLSQCVLYYTRVKVVVLMDLE 129

  Fly   104 VVNPGAEVKSKIGEPVTY----------ENAAKQDLAPKPAVTSNSKPIAKKEPSHNNNNNIVMN 158
            |:....:|..|||.||.|          :...:|...|.|| ::.:.|.:|.:|   .|.::.|.
Mouse   130 VMKSAEDVGLKIGNPVPYNEGYGQQQQQQQQQQQQAVPSPA-SAATPPASKPQP---QNGSLGMG 190

  Fly   159 SSI--------------------NSGMTH----PISSLSPYQNKWVIKARVTSKSGIRTWSNARG 199
            |:.                    .||.|.    ||:||:|||:||.|.||||:||.||||||:||
Mouse   191 STAAKAYGASKPFGKPAGTGLLQPSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRG 255

  Fly   200 EGKLFSMDLMDESGEIRATAFKEQCDKFYDLIQVDSVYYISKCQLKPANKQYSSLNNAYEMTFSG 264
            ||||||::|:|||||||||||.||.|||:.||:|:.|||.||..||.||||:|::.|.|||||:.
Mouse   256 EGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGALKIANKQFSAVKNDYEMTFNN 320

  Fly   265 ETVVQLCEDTDDDPIPEIKYNLVPISDVSGMENKAAVDTIGICKEVGELQSFVARTTNKEFKKRD 329
            ||.|..||  |...:|.::::...|.|:......|.||.|||||...:......::.|:|..||:
Mouse   321 ETSVLPCE--DGHHLPTVQFDFTGIGDLESKAKDALVDIIGICKSYEDSIKITVKSNNREVAKRN 383

  Fly   330 ITLVDMSNSAISLTLWGDDAVNFDGHVQPVILVKGTRINEFNGGKSLSLGGGSIMKINPDIPEAH 394
            |.|:|||...::.||||:||..|||..|||:.:||.|:::| ||:|||:...|.:.:|||||||:
Mouse   384 IYLMDMSGKVVTTTLWGEDADKFDGSRQPVMAIKGARVSDF-GGRSLSVLSSSTVIVNPDIPEAY 447

  Fly   395 KLRGWFDNGG----GDSVANMVSARTGGGSFSTEWMTLKDARARNLGSGDKPDYFQCKAVVHIVK 455
            |||||||:.|    |.|:::..|...|||  :|.|.||.:|::.|||.|||.|||...|.|..::
Mouse   448 KLRGWFDSEGQALDGVSISDHRSGGAGGG--NTNWKTLHEAKSENLGQGDKADYFSTVAAVVFLR 510

  Fly   456 QENAFYRACPQSDCNKKVVDEGNDQFRCEKCNALFPNFKYRLLINMSIGDWTSNRWVSSFNEVGE 520
            :||..|:|||..||||||:|:.|..:|||||:..|||||||::::.:|.|:..|:||:.|.|..|
Mouse   511 KENCMYQACPTQDCNKKVIDQQNGLYRCEKCDREFPNFKYRMILSANIADFQENQWVTCFQESAE 575

  Fly   521 QLLGHTSQEVGEALENDPAKAEQIFSALNFTSHIFKLRCKNEVYGDMTRNKLTVQSVAPINHKEY 585
            .:||..:..:||..|.:....|::|...||.|..|::|.|.|.|.|.:|.|.||..|.|::.::|
Mouse   576 AILGQNTMYLGELKEKNEQAFEEVFQNANFRSFTFRIRVKLETYNDESRIKATVMDVKPVDFRDY 640

  Fly   586 NKHLLKELQE 595
            .:.|:..:::
Mouse   641 GRRLIANIRK 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RPA1	NP_524274.1	rpa1	3..595	CDD:273177	266/657 (40%)
Rpa1	XP_006534114.1	rpa1	2..650	CDD:273177	266/657 (40%)