Protein Alignment RpA-70 and rpa1

DIOPT Version :9

• Sequence 1: NP_524274.1
• Gene: RpA-70 / 40972
• FlyBaseID: FBgn0010173
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001015732.1
• Gene: rpa1 / 548449
• XenbaseID: XB-GENE-945047
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 617
• Identity: 267/617 - (43%)
• Similarity: 380/617 - (61%)
• Gaps: 26/617 - (4%)

  Fly     1 MVLASLSTGVIARIMHGEVVDAPVLQILAIKKINSAADSERYRILISDGKYFNSYAMLASQLNVM 65
            |.|..||.|.|:.|:.|:....|.||::.|:.||:.....|||:|:|||....|..|||:|||.:
 Frog     1 MALPVLSEGAISAILGGDSSCKPTLQVINIRSINTGNGPPRYRLLMSDGLNTLSSFMLATQLNFL 65

  Fly    66 QHNGELEEFTIVQLDKYVTSLVGKDGAGKRVLIISELTVVNPGAEVKSKIGEPVTYEN--AAKQD 128
            ..|..|....|.|:.:::.:.: ||  |:||:|:.|:.|:.....||.|||.|..|.:  ...|.
 Frog    66 VDNNLLATNCICQVSRFIVNNL-KD--GRRVIIVMEMEVLKSADLVKGKIGNPHPYNDGQGPPQP 127

  Fly   129 LAPKPA-VTSNSKP---IAKKEPSHN-------NNNNIVMNSSINSGMTHPISSLSPYQNKWVIK 182
            .||.|| ....|||   .|...||.|       ...::|.....:.....||:||:|||:||.::
 Frog   128 AAPAPASAPPPSKPQNISAPPPPSMNRGASKLFGGGSVVNTPGGSQSKVVPIASLNPYQSKWTVR 192

  Fly   183 ARVTSKSGIRTWSNARGEGKLFSMDLMDESGEIRATAFKEQCDKFYDLIQVDSVYYISKCQLKPA 247
            ||||:|..||||||:||||||||::::|||||||||||.||.|||:.||:|:.|||.||..||.|
 Frog   193 ARVTNKGQIRTWSNSRGEGKLFSIEMVDESGEIRATAFNEQADKFFSLIEVNKVYYFSKGTLKIA 257

  Fly   248 NKQYSSLNNAYEMTFSGETVVQLCEDTDDDPIPEIKYNLVPISDVSGMENKAAVDTIGICKEVGE 312
            ||||:|:.|.|||||:.||.|..|:|:.|  :|.:::..|||.::........:|.|||||...|
 Frog   258 NKQYTSVKNDYEMTFNSETSVIPCDDSAD--VPMVQFEFVPIGELESKNKDTVLDIIGICKNAEE 320

  Fly   313 LQSFVARTTNKEFKKRDITLVDMSNSAISLTLWGDDAVNFDGHVQPVILVKGTRINEFNGGKSLS 377
            :.....|:.|:|..||:|.|:|.|...:|.||||:||..|||..|||:.:||.|:::| ||:|||
 Frog   321 VTKVTIRSNNREVSKRNINLMDSSGKVVSTTLWGEDADKFDGSRQPVVAIKGARLSDF-GGRSLS 384

  Fly   378 LGGGSIMKINPDIPEAHKLRGWFDNGG----GDSVANMVSARTGGGSFSTEWMTLKDARARNLGS 438
            :...|.:.||||||||.|||.|||:.|    |.|::   .:|.|.|..:|.|.:|.:.:..|||.
 Frog   385 VLSSSTVMINPDIPEAFKLRAWFDSEGQVVEGTSIS---ESRGGTGGGNTNWKSLLEVKTENLGH 446

  Fly   439 GDKPDYFQCKAVVHIVKQENAFYRACPQSDCNKKVVDEGNDQFRCEKCNALFPNFKYRLLINMSI 503
            |:|.|||...|.:..:::||..|:|||..||||||:|:.|..||||||:..|||:||||:::.:|
 Frog   447 GEKADYFTSVATIVYLRKENCLYQACPSQDCNKKVIDQQNGLFRCEKCDKEFPNYKYRLILSANI 511

  Fly   504 GDWTSNRWVSSFNEVGEQLLGHTSQEVGEALENDPAKAEQIFSALNFTSHIFKLRCKNEVYGDMT 568
            .|:..|:|::.|.|..|.:||..:..:||..|.:....:::|...||.|:.|::|.|.|.|.|.:
 Frog   512 ADFGENQWITCFQESAESILGQNATYLGELKEKNEQAYDEVFQNANFRSYTFRIRVKLETYNDES 576

  Fly   569 RNKLTVQSVAPINHKEYNKHLLKELQELTGIG 600
            |.|.|...|.|::||||::.|:..::::...|
 Frog   577 RIKATAMDVKPVDHKEYSRRLIMNIRKMAAQG 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpA-70	NP_524274.1	rpa1	3..595	CDD:273177	265/608 (44%)
		Rep-A_N	6..107	CDD:281980	38/100 (38%)
		RPA1_DBD_A	168..270	CDD:239920	69/101 (68%)
		RPA1_DBD_B	301..401	CDD:239921	51/99 (52%)
		Rep_fac-A_C	444..589	CDD:285809	61/144 (42%)
rpa1	NP_001015732.1	rpa1	3..603	CDD:273177	265/608 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..164		16/51 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I4509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2208
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1320
OMA	1	1.010	-	-		QHG54397
OrthoDB	1	1.010	-	-		D1189265at2759
OrthoFinder	1	1.000	-	-		FOG0002228
OrthoInspector	1	1.000	-	-		otm49304
Panther	1	1.100	-	-	LDO	PTHR23273
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2748
SonicParanoid	1	1.000	-	-		X1901
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110