Protein Alignment RpA-70 and rpa1

DIOPT Version :9

• Sequence 1: NP_524274.1
• Gene: RpA-70 / 40972
• FlyBaseID: FBgn0010173
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_956105.2
• Gene: rpa1 / 327491
• ZFINID: ZDB-GENE-030912-3
• Length: 601
• Species: Danio rerio
• Alignment Length: 609
• Identity: 256/609 - (42%)
• Similarity: 378/609 - (62%)
• Gaps: 33/609 - (5%)

  Fly     6 LSTGVIARIMHGEVVDAPVLQILAIKKINSAADSERYRILISDGKYFNSYAMLASQLNVMQHNGE 70
            ||.|.|..:..|..|:.|:||.:.|:||:......|:|:::|||.:..|..||::|||.|....:
Zfish     5 LSEGAIESLSKGTEVNNPILQCVNIRKIDGGNGVSRFRVMMSDGLHTMSSFMLSTQLNPMAEQNQ 69

  Fly    71 LEEFTIVQLDKYVTSLVGKDGAGKRVLIISELTVVNPGAEVKSKIGEPVTYENAAKQDLAPKPAV 135
            |....:..|.:.||::: ||  |:||::|.::.|:....::..|||:|..|...  |..||..|.
Zfish    70 LATNCVCVLKRSVTNVL-KD--GRRVVVILDIEVLKSADQMPGKIGDPTPYVEG--QSKAPSTAP 129

  Fly   136 TSNSKPIAKKEPSHNNNNN--------------IVMNSSINSGMTHPISSLSPYQNKWVIKARVT 186
            ...::|:   :|.:.::.:              ...|:...|....||:||:|||:||.|:||||
Zfish   130 APTARPL---QPQNGSDGSTYRPSAQSFGKKPMAAPNTPGGSSKVVPIASLNPYQSKWTIRARVT 191

  Fly   187 SKSGIRTWSNARGEGKLFSMDLMDESGEIRATAFKEQCDKFYDLIQVDSVYYISKCQLKPANKQY 251
            :||.||||||:||:||||||:|:|||||||||.|..:.|||:.||:...|:||||..||.||||:
Zfish   192 NKSAIRTWSNSRGDGKLFSMELVDESGEIRATGFNNEVDKFFSLIEQGKVFYISKGTLKIANKQF 256

  Fly   252 SSLNNAYEMTFSGETVVQLCEDTDDDPIPEIKYNLVPISDVSGMENKAAVDTIGICKEVGELQSF 316
            |||.|.||||.:|||.:..|||::|  :|.::.:.|.|:|:...|....:|.||:||...::...
Zfish   257 SSLKNDYEMTLNGETSIIPCEDSND--VPMLQCDFVSIADLESREKDTILDVIGVCKNAEDVARI 319

  Fly   317 VARTTNKEFKKRDITLVDMSNSAISLTLWGDDAVNFDGHVQPVILVKGTRINEFNGGKSLSLGGG 381
            :.: .::|..||:|.|:|||...|.||:||.||..|||..||::.:||.|:::| ||:|||....
Zfish   320 MTK-NSREVSKRNIQLIDMSGRVIQLTMWGSDAETFDGSGQPILAIKGARLSDF-GGRSLSTLYS 382

  Fly   382 SIMKINPDIPEAHKLRGWFDNGG----GDSVANMVSARTGGGSFSTEWMTLKDARARNLGSGDKP 442
            |.:.||||||||:|||||:|..|    |.|   |...|..||..:|.|.||.:.:..:||.|||.
Zfish   383 STVMINPDIPEAYKLRGWYDKEGHALDGQS---MTELRGPGGGGNTNWKTLAEVKNEHLGHGDKA 444

  Fly   443 DYFQCKAVVHIVKQENAFYRACPQSDCNKKVVDEGNDQFRCEKCNALFPNFKYRLLINMSIGDWT 507
            |||.|.|.:..:::||..|:|||..||||||||:.|..||||||:..||:|||||:::.:|.|:.
Zfish   445 DYFSCIATIVYIRKENCLYQACPSKDCNKKVVDQQNGMFRCEKCDKEFPDFKYRLMLSANIADFG 509

  Fly   508 SNRWVSSFNEVGEQLLGHTSQEVGEALENDPAKAEQIFSALNFTSHIFKLRCKNEVYGDMTRNKL 572
            .|:||:.|.:..|.|||..|..:|:..:.:.|..:::|...||.:.:|:.|.|.|.|.|.:|.|:
Zfish   510 DNQWVTCFQDTAETLLGQNSSYLGQLKDTNEAAFDEVFQHANFNTFVFRNRVKLETYNDESRIKV 574

  Fly   573 TVQSVAPINHKEYNKHLLKELQEL 596
            ||....|::|:||:|.|:..:::|
Zfish   575 TVVDAKPVDHREYSKRLIINIRKL 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpA-70	NP_524274.1	rpa1	3..595	CDD:273177	255/606 (42%)
		Rep-A_N	6..107	CDD:281980	35/100 (35%)
		RPA1_DBD_A	168..270	CDD:239920	68/101 (67%)
		RPA1_DBD_B	301..401	CDD:239921	48/99 (48%)
		Rep_fac-A_C	444..589	CDD:285809	63/144 (44%)
rpa1	NP_956105.2	rpa1	3..597	CDD:273177	255/606 (42%)
		RPA1N	8..102	CDD:239923	33/96 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	107..172		13/69 (19%)
		RPA1_DBD_A	173..275	CDD:239920	68/101 (67%)
		REPA_OB_2	292..388	CDD:293505	38/97 (39%)
		Rep_fac-A_C	446..591	CDD:285809	63/144 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590631
Domainoid	1	1.000	150	1.000	Domainoid score	I4362
eggNOG	1	0.900	-	-		E1_COG1599
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2208
Inparanoid	1	1.050	487	1.000	Inparanoid score	I1388
OMA	1	1.010	-	-		QHG54397
OrthoDB	1	1.010	-	-		D1189265at2759
OrthoFinder	1	1.000	-	-		FOG0002228
OrthoInspector	1	1.000	-	-		oto39100
orthoMCL	1	0.900	-	-		OOG6_101316
Panther	1	1.100	-	-	LDO	PTHR23273
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2748
SonicParanoid	1	1.000	-	-		X1901
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800