DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpA-70 and R03H10.7

DIOPT Version :9

Sequence 1:	NP_524274.1	Gene:	RpA-70 / 40972	FlyBaseID:	FBgn0010173	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_494734.3	Gene:	R03H10.7 / 187559	WormBaseID:	WBGene00019859	Length:	359	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	66/243 - (27%)
Similarity:	115/243 - (47%)	Gaps:	24/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 PISSLSPYQNKWVIKARVTSKSGIRTWSNARGEGKLFSMDLMDESGE-IRATAFKEQCDKFYDLI 231
            ||.:|....|.:.|..|||    :..........|.|:.::.|.:|: |..:|...:.|.||..:
Worm   116 PIENLKESVNYFKIHGRVT----LMDTRPPHHYQKRFNFEITDFNGDTIACSASSPEADVFYQNL 176

  Fly   232 QVDSVYYISKCQLKPANKQYSSLNNAYEMTFSGETVVQLCEDTDDDPIPEI----KYNL--VPIS 290
            ..:..||::...:|..::.|:.....|::..:..|::        :|.|.:    |:|:  |.:|
Worm   177 VKEQSYYLAGGHIKKGHEIYNQTGIDYQIDLNNFTIM--------EPAPTLLTLPKFNIQRVFLS 233

  Fly   291 DVSGMENKAAVDTIGICKEVGELQSFVARTTNKEFKKRDITLVDMSNSAISLTLWGDDAVNF--D 353
            ||:.:  |..:|.:...||..:::::.. |.||...||.|.::|.|.|.|..|.||.:||:.  :
Worm   234 DVANV--KKPIDVLVCIKEFKDVENYTP-TENKPPHKRHIQVIDDSKSEIRATFWGYNAVDAIRE 295

  Fly   354 GHVQPVILVKGTRINEFNGGKSLSLGGGSIMKINPDIPEAHKLRGWFD 401
            ..:..|:..||....|.||...||:..|:.:.|.|::..|..|..|||
Worm   296 EFLNKVVAFKGVIPTEGNGQLFLSITPGTRIVIQPEVDGAAYLEAWFD 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpA-70	NP_524274.1	rpa1	3..595	CDD:273177	66/243 (27%)
		Rep-A_N	6..107	CDD:281980
		RPA1_DBD_A	168..270	CDD:239920	23/102 (23%)
		RPA1_DBD_B	301..401	CDD:239921	32/101 (32%)
		Rep_fac-A_C	444..589	CDD:285809
R03H10.7	NP_494734.3	RPA_2b-aaRSs_OBF_like	7..101	CDD:385638
R03H10.7	NP_494734.3	rpa1	<106..>355	CDD:273177	66/243 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1189265at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750