Protein Alignment RPA1 and RpA-70

DIOPT Version :10

• Sequence 1: NP_524274.1
• Gene: RPA1 / 40972
• FlyBaseID: FBgn0010173
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_321709.5
• Gene: RpA-70 / 1281755
• VectorBaseID: AGAMI1_014805
• Length: 612
• Species: Anopheles gambiae
• Alignment Length: 613
• Identity: 345/613 - (56%)
• Similarity: 458/613 - (74%)
• Gaps: 22/613 - (3%)

  Fly     6 LSTGVIARIMHGEVVDAPVLQILAIKKI-NSAADSERYRILISDGKYFNSYAMLASQLNVMQHNG 69
            |:.|.:|.||.|..:..||:|||..|:| .:...|||:|:||||||...|:||||:|||.:|...
Mosquito     6 LTVGFLAEIMQGNELQNPVVQILGSKRIAGNGEQSERFRLLISDGKSLYSFAMLATQLNDLQKQD 70

  Fly    70 ELEEFTIVQLDKYVTSLVGKDGAG-KRVLIISELTVVNPGAEVKSKIGEPVTYENAAKQDLAPKP 133
            :|.::||:::|:|.||:|.::..| ||||||.||||:..|:.|..|||:|     ....|...:|
Mosquito    71 KLPQYTIIRIDRYTTSVVNRNEKGEKRVLIIVELTVLKEGSLVGEKIGDP-----QPMTDTPSQP 130

  Fly   134 AVT-SNSKPIAKKEPSHNNNNNI-VMNSSINSG-----------MTHPISSLSPYQNKWVIKARV 185
            |.| :.::|:.....|..|..:. .:|.|::.|           :||||||||||||||||||||
Mosquito   131 ATTQAPARPMDTGSSSMGNGGSYGSVNRSLSGGSAGPTQSIGDSLTHPISSLSPYQNKWVIKARV 195

  Fly   186 TSKSGIRTWSNARGEGKLFSMDLMDESGEIRATAFKEQCDKFYDLIQVDSVYYISKCQLKPANKQ 250
            .|||||||||||:|||||||||:||||||||.||||||||::||:|:||.||:||||||||||||
Mosquito   196 MSKSGIRTWSNAKGEGKLFSMDVMDESGEIRITAFKEQCDRYYDMIEVDKVYFISKCQLKPANKQ 260

  Fly   251 YSSLNNAYEMTFSGETVVQLCEDTDDDPIPEIKYNLVPISDVSGMENKAAVDTIGICKEVGELQS 315
            |:||.|.||||.:.:|:||.|:|.|.. :|||:||.||||.::.||..|.||.||:||:..::..
Mosquito   261 YTSLKNDYEMTMTNDTIVQECKDADGS-MPEIQYNFVPISQIANMEPNAMVDVIGMCKDASDVVQ 324

  Fly   316 FVARTTNKEFKKRDITLVDMSNSAISLTLWGDDAVNFDGHVQPVILVKGTRINEFNGGKSLSLGG 380
            |.|:|:.:|.:||:|||||.||:::.||||||||.||.....||:|:||.|::||.|||||.|.|
Mosquito   325 FTAKTSGRELRKREITLVDSSNASVQLTLWGDDAQNFPATTHPVVLLKGARVSEFGGGKSLGLIG 389

  Fly   381 GSIMKINPDIPEAHKLRGWFDNGGGDSVANMVSARTGGGS-FSTEWMTLKDARARNLGSGDKPDY 444
            ||:||:|||:..|||:||||:|||.::..:.|||||||.: .||||::.::|:.:|||:||||||
Mosquito   390 GSVMKLNPDLEMAHKVRGWFENGGSEASVSSVSARTGGAAGVSTEWLSFQEAKDKNLGAGDKPDY 454

  Fly   445 FQCKAVVHIVKQENAFYRACPQSDCNKKVVDEGNDQFRCEKCNALFPNFKYRLLINMSIGDWTSN 509
            ||.||::|.:|..||.|:||||:||||||:|:.|.|||||||||.|||||||||:||.|||||||
Mosquito   455 FQVKAMIHTIKSANAVYKACPQADCNKKVIDQENGQFRCEKCNAEFPNFKYRLLVNMLIGDWTSN 519

  Fly   510 RWVSSFNEVGEQLLGHTSQEVGEALENDPAKAEQIFSALNFTSHIFKLRCKNEVYGDMTRNKLTV 574
            |||:.|.|:.|::||.:|||:|.:||....:||::|::::|.|.:||||.|.|.:|:..|||.:.
Mosquito   520 RWVTVFTELAEEMLGKSSQEIGSSLEYQKEEAEKLFTSISFKSFVFKLRTKVEYFGEQPRNKTSA 584

  Fly   575 QSVAPINHKEYNKHLLKELQELTGIGSS 602
            .||||:||||||..|:|.:|||||:|.:
Mosquito   585 VSVAPVNHKEYNALLIKSIQELTGVGKN 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RPA1	NP_524274.1	rpa1	3..595	CDD:273177	339/604 (56%)
RpA-70	XP_321709.5	None