DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9636 and Cuedc2

DIOPT Version :9

Sequence 1:	NP_649774.1	Gene:	CG9636 / 40967	FlyBaseID:	FBgn0037556	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001157762.1	Gene:	Cuedc2 / 67116	MGIID:	1914366	Length:	284	Species:	Mus musculus

Alignment Length:	302	Identity:	86/302 - (28%)
Similarity:	154/302 - (50%)	Gaps:	37/302 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MVKRSLVQFISGHIPGADFSVVDEIVLSYIISILEE----ASQDPCFDVEGFVEMMGAYFEEFST 70
            :|..:|:.|:..|:|.||.|.:||::.||::.:||:    ...:..||:|.|.|||.||...|:.
Mouse     6 IVGSALLTFVQAHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFTEMMEAYVPGFAH 70

  Fly    71 IDQGIICDWIYKLANELTDMEKTQENPDAVNLSLNSLSLSS---IIPESKLRARNSSTSEKDELS 132
            |.:|||.|.:.||:.:|:|....:      ||...|..:..   |.||:..:|      ||.|..
Mouse    71 IPRGIIGDMMQKLSVQLSDARNKE------NLHPQSSCVQGQVPIFPETPRQA------EKLEEE 123

  Fly   133 SNSSSSGGCGGNKRSQHLSETSDGGSTDSSSSTCDYFLDETEVLQEMFPDSAIAEIKHCIAISKG 197
            |...:                :.|.:.|.:::..:  |...:||.|:||..::.:.:..:|.::|
Mouse   124 SRPPA----------------APGNTLDEAAAAEE--LPGVDVLLEVFPTCSMEQAQWVLAKARG 170

  Fly   198 DIDSATQILLHRQETNQCITDKSHTTYMKKNVIVDDNELKNRIIARYSYVDKNATQREYKPVVPK 262
            |::.|..:|:..:|......|.......::......::||:.|:.:|..||:...|:.::|:.||
Mouse   171 DLEEAVHMLVEGKEEGPPGWDGPSQDLPRRLRGPQKDDLKSFILQKYMMVDRAEDQKTHRPMAPK 235

  Fly   263 MEPRKLVRYRDNKIVSLKGERYTEIKRDEDAELKKPKKQIQP 304
            ..|:||:||.||::||.||||:.:::..|..|:|.....::|
Mouse   236 EAPKKLIRYIDNQVVSTKGERFKDVRNPEAEEMKATYINLKP 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9636	NP_649774.1	CUE_CUED2	169..210	CDD:270550	11/40 (28%)
Cuedc2	NP_001157762.1	CUE_CUED2	144..183	CDD:270550	10/38 (26%)
Cuedc2	NP_001157762.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	183..204		2/20 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BVVF
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11430
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4651
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47001
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008394
OrthoInspector	1	1.000	-	-		oto92609
orthoMCL	1	0.900	-	-		OOG6_109461
Panther	1	1.100	-	-	LDO	PTHR12493
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5269
SonicParanoid	1	1.000	-	-		X6383
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790