DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9636 and cuedc2

DIOPT Version :9

Sequence 1:	NP_649774.1	Gene:	CG9636 / 40967	FlyBaseID:	FBgn0037556	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001017994.1	Gene:	cuedc2 / 334351	ZFINID:	ZDB-GENE-030131-6283	Length:	282	Species:	Danio rerio

Alignment Length:	302	Identity:	93/302 - (30%)
Similarity:	159/302 - (52%)	Gaps:	37/302 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EMVKRSLVQFISGHIPGADFSVVDEIVLSYIISILEE-ASQDPC---FDVEGFVEMMGAYFEEFS 69
            :::..:|..||..:||.||.|.:|:::||||..:||: .||:..   ||||.||||:.||...||
Zfish     5 KIIHDALYDFILSYIPHADLSTLDDVILSYITGVLEDLGSQESVEENFDVEVFVEMLEAYIPGFS 69

  Fly    70 TIDQGIICDWIYKLANELTDMEKTQENPDAVNLSLNSLSLSSIIPESKLRARNSSTSEKDELSSN 134
            .||...:|:.::.||.:||....|:..                  |.|:.......||..:||
Zfish    70 DIDSVKVCEMMFNLAAKLTSARDTESG------------------EMKIEEGKFPLSESCDLS-- 114

  Fly   135 SSSSGGCGGNKRSQH-LSETSDGGSTDSSSSTCDYFLDETEVLQEMFPDSAIAEIKHCIAISKGD 198
                  .||::...| |:..::|.:...|.|:.|   ::.:.|.||||..::.|.:..::|:|||
Zfish   115 ------LGGSREKTHNLTLQAEGATAQVSESSWD---NQEQHLLEMFPKCSVTEARSALSIAKGD 170

  Fly   199 IDSATQILLHRQETNQCITDKSHTTYMKKNVIVD-DNELKNRIIARYSYVDKNATQREYKPVVPK 262
            ::.|.::::......:|  ..|.:....|.|..: |.:||..|:.:|..||....::.::||.||
Zfish   171 MEEAVRLIIEGDVQLKC--PPSLSANQGKTVSAEVDQKLKASILEKYMLVDDEEDKKVHRPVTPK 233

  Fly   263 MEPRKLVRYRDNKIVSLKGERYTEIKRDEDAELKKPKKQIQP 304
            ..|:|:|||..:::|:.|||||..:|::|..::||....::|
Zfish   234 DAPKKMVRYHGSQVVTTKGERYHLVKKEEPEDMKKTYVSLKP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9636	NP_649774.1	CUE_CUED2	169..210	CDD:270550	11/40 (28%)
cuedc2	NP_001017994.1	CUE_CUED2	141..182	CDD:270550	12/43 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BVVF
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11430
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4418
OMA	1	1.010	-	-		QHG47001
OrthoDB	1	1.010	-	-		D1410219at2759
OrthoFinder	1	1.000	-	-		FOG0008394
OrthoInspector	1	1.000	-	-		oto39266
orthoMCL	1	0.900	-	-		OOG6_109461
Panther	1	1.100	-	-	LDO	PTHR12493
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5269
SonicParanoid	1	1.000	-	-		X6383
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800