DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ada2b and YOR338W

DIOPT Version :9

Sequence 1:	NP_001027151.1	Gene:	Ada2b / 40966	FlyBaseID:	FBgn0037555	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_014983.1	Gene:	YOR338W / 854516	SGDID:	S000005865	Length:	363	Species:	Saccharomyces cerevisiae

Alignment Length:	293	Identity:	62/293 - (21%)
Similarity:	101/293 - (34%)	Gaps:	75/293 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 QLGYMPN---------RDSFEREYDPTAEQLISNISLSSEDTEVDVMLKLAHVD---IYTRRLRE 221
            ::||..|         |::.|...: :.|.....||.||....:|     |.:|   |.:..|..
Yeast    29 KIGYKLNQQVQRLAVVRNNIEERLN-SMESSHGQISDSSVVRAID-----ASIDDFLIPSPPLSP 87

  Fly   222 RARRKRMVRDYQLVSNFFRNRNYAQ-----QQGLTKEQ-----REFRDRFRVYAQFYTC----NE 272
            :.|:..::...|||:....:|....     :.||..::     |.|..::..:....|.    |:
Yeast    88 KLRQCPIISQPQLVNVESDHRELIMLTPVWEAGLNSQKYNHNTRNFLSQYSFFRDMKTTKRIPNK 152

  Fly   273 YERLLGSLER-------------EKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGP 324
            ..|.|..::.             :::::.|..|||....|     ....:.|:.|.....||..|
Yeast   153 ENRKLKVVKSVVNSEALPKRRRYDRKIKRRSRELYEDDGN-----RSENYDEESAQEVPVRSVTP 212

  Fly   325 YGHGKTD-HTHTS--------NG--------------SHRPPSSSLHSPQPNLRKVEMSSGGEAS 366
            ....|.. ||.:|        |.              .:.||..:|.:....:.|||. .|....
Yeast   213 IRQVKRSLHTISSPLASQGVVNNVPKYIPSMSWEKLPDYSPPLHTLPNSNNKVLKVEW-KGSPMD 276

  Fly   367 SNSIAPRNTLHIADPTCSGAL-LPSKNYLDSCR 398
            .|....:..||.|:...:..| ||...||||.|
Yeast   277 LNHDPLKQRLHPAELVLAQILRLPCDLYLDSKR 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	43/233 (18%)
		ZZ_ADA2	11..58	CDD:239075
		SANT	73..115	CDD:238096
YOR338W	NP_014983.1	SWIRM	285..354	CDD:398234	11/25 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12374
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100