Protein Alignment Ada2b and tada2a

DIOPT Version :9

• Sequence 1: NP_001027151.1
• Gene: Ada2b / 40966
• FlyBaseID: FBgn0037555
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_005157493.1
• Gene: tada2a / 797303
• ZFINID: ZDB-GENE-060929-508
• Length: 445
• Species: Danio rerio
• Alignment Length: 584
• Identity: 136/584 - (23%)
• Similarity: 214/584 - (36%)
• Gaps: 185/584 - (31%)

  Fly     6 DLFTKYNCTNCQDDIQGIRVHCAEC--ENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVF 68
            |.|.|..|..|...:....:.||||  ..|.||||||..|.|...||::|.|:.|.:...:|
Zfish    10 DPFDKPPCRGCSSYLVEPYIKCAECGPSPFLLCLQCFTRGYEYKKHQSDHKYEIMTSDFPVL--- 71

  Fly    69 RGKGAWTAREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNGTIGRATWTPAQSQ 133
              :..|||:||:.||:|:...|||||:|::..:.:|:.|:.:..|:..::|..:..:|....:
Zfish    72 --ESGWTAQEEMALLEAVMDCGFGNWQDVAYQMRSKTKEECEGHYMKNYINNPLFSSTLLSLR-- 132

  Fly   134 RPRLIDH---TGD--------DDAGPLGTNALSTLPP-----LEINSDEAMQLGYMPNRDSFERE 182
              .:.||   |.|        ||            ||     .:::.|.|   ||||.|..|..|
Zfish   133 --HMDDHLSRTADTAIPFKPTDD------------PPRPSFDSQLSRDMA---GYMPARADFMEE 180

  Fly   183 YDPTAEQLISNISLSSEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVS---NFFRNRNY 244
            :|..||..:.:|....:|:::...||:|.||||..||:||.|||:::||:.|::   .....|.|
Zfish   181 FDNYAEWDLKDIDFVDDDSDILHALKVAVVDIYHSRLKERQRRKKIIRDHGLINLRKFLILERRY 245

  Fly   245 AQQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTH 309
                  .||.::..|..|.:|:.....|:::.:.|...|.|||.....|..||..|:........
Zfish   246 ------PKEVQDLYDVMRRFARVVGPIEHDKFIESHTLEFELRREIHRLQEYRSEGIQSFCGAKV 304

  Fly   310 FEQHAATATHRSTGPYGHGKTDHTHTSNGSHRPPSSSLHSPQPNLRKVEMSSGGEASSNSIAPRN 374
            :|:...|.                                 :...||..|
Zfish   305 YERVKRTR---------------------------------EDERRKRNM--------------- 321

  Fly   375 TLHIADPTCSGALLPSKNYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPTNS 439
                        |.....|:...|........|       ..:|:|....|::.:|:
Zfish   322 ------------LCDVLQYIHDTRACQQWLHKQ-------AAIDAGIAPVVSTISTS-------- 359

  Fly   440 AKGSQQHLQPLQQHPQLLQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLPQPPGSELLS 504
                                             |....|.::|   |.|         ||:|.|:
Zfish   360 ---------------------------------GRRSAPPLNL---TGL---------PGTEKLN 379

  Fly   505 HNELDLCKKHNITPTTYLSVKTVCLSGAPSLG--------SPMETSLRK------FFIKCGWLS 554
            ..|.:||:...:.|..||..|...|:.....|        |.::..:.|      |.||.|:::
Zfish   380 EREKELCQVVRLVPGAYLEYKQALLNECRRQGGLRLAQARSLIKIDVNKTRKIYDFLIKEGYIN 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	99/351 (28%)
		ZZ_ADA2	11..58	CDD:239075	19/48 (40%)
		SANT	73..115	CDD:238096	17/41 (41%)
tada2a	XP_005157493.1	ZZ_ADA2	15..64	CDD:239075	19/48 (40%)
		COG5114	28..442	CDD:227445	131/563 (23%)
		SANT	75..117	CDD:238096	17/41 (41%)
		SWIRM	376..443	CDD:282311	17/66 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D570949at33208
OrthoFinder	1	1.000	-	-		FOG0001650
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100940
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R21
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750