Protein Alignment Ada2b and tada2b

DIOPT Version :9

• Sequence 1: NP_001027151.1
• Gene: Ada2b / 40966
• FlyBaseID: FBgn0037555
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001019614.1
• Gene: tada2b / 554156
• ZFINID: ZDB-GENE-050522-557
• Length: 486
• Species: Danio rerio
• Alignment Length: 606
• Identity: 184/606 - (30%)
• Similarity: 265/606 - (43%)
• Gaps: 179/606 - (29%)

  Fly     4 IADLFTKYNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVF 68
            :|||..|| |.||..|:..:|:.||||::.:||.:||:||||||.|:..|.||.:|.|...|...
Zfish     1 MADLGKKY-CVNCLADVTNLRIRCAECQDIELCPECFSAGAEIGNHRRWHGYQQVDGGRFSLWGP 64

  Fly    69 RGKGAWTAREEIRLLDAIEQYGFGNWEDISKHI-ETKSAEDAKEEYVNKFVNGTIGRATWTPAQS 132
            ..:|.||:|||..|||||||||||||||::.|: .:::.::..:.||:.:::|.:|:|. .| .|
Zfish    65 EAEGGWTSREEQSLLDAIEQYGFGNWEDMAAHVGASRTPQEVMDHYVSMYIHGNLGKAC-IP-DS 127

  Fly   133 QRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNISLS 197
            ...|:.||| ....|||..:..:.||||:|...|..||||||.||.:|.|||..||:|||.:|::
Zfish   128 IPNRVTDHT-CPSGGPLSPSLTTPLPPLDITVVEQQQLGYMPLRDDYEIEYDQEAEKLISGLSVN 191

  Fly   198 SEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFF------RNRNYA----------- 245
            .:|.::::.:|.||||:|.|:||||.|||.:.|||.||..|.      :.|..|
Zfish   192 YDDEDIEIEMKRAHVDMYVRKLRERQRRKNIARDYNLVPAFLGRDKKDKERERAGGTVGVGGPGG 256

  Fly   246 -----------------------QQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLEREKELR 287
                                   .::.:|||::..|.:.|...||....|:|....::.:|:.||
Zfish   257 AVGSGSGATVVPAGPLGSSTAATPKRKITKEEKGQRTKLRALCQFMPQREFEEFFDNMHKERMLR 321

  Fly   288 IRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGPYGHGKTDHTHTSNGSHRPPSSSLHSPQP 352
            .:..||.|||.||:|::.|...:|    .|.|:      ..|.....:..||.|.
Zfish   322 AKVRELQRYRRNGITRLDESAEYE----AARHK------REKRKENKSIAGSKRG---------- 366

  Fly   353 NLRKVEMSSGGEASSNSIAPRNTLHIADPTCSGALLPSKNYLDSCRGSSAATMLQTTGMVMGVTV 417
                   ||||...                                         |.|:..||
Zfish   367 -------SSGGGGG-----------------------------------------TAGLGGGV-- 381

  Fly   418 DSGATTGVTSTATTMANLPTNSAKGSQQHLQPLQQHPQLLQSGNQHKMQNEAAGGGSDQVPSMSL 482
              ||..|:                                           ..|||..     ::
Zfish   382 --GAGGGL-------------------------------------------GGGGGVS-----TI 396

  Fly   483 KLRTQLEELKHLPQPPGSELLSHNELDLCKKHNITPTTYLSVKTVCL-------SGAPS---LGS 537
            |...:..|...:....|.||||..|..||...|::|..||:|||:.:       .|.||   |.|
Zfish   397 KEEGKDSEFSAIENLSGFELLSDREKVLCNSMNLSPMRYLTVKTIIIKDHLQKRQGIPSKSRLPS 461

  Fly   538 PMETSLRK----FFIKCGWLS 554
            .::..|:|    |..:.||:|
Zfish   462 YLDKVLKKRILNFLSESGWIS 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	138/371 (37%)
		ZZ_ADA2	11..58	CDD:239075	24/46 (52%)
		SANT	73..115	CDD:238096	22/42 (52%)
tada2b	NP_001019614.1	COG5114	6..481	CDD:227445	179/598 (30%)
		ZZ_ADA2	7..54	CDD:239075	25/47 (53%)
		SANT	70..113	CDD:238096	23/42 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	237..291		5/53 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	343..377		12/101 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595644
Domainoid	1	1.000	171	1.000	Domainoid score	I3709
eggNOG	1	0.900	-	-		E1_COG5114
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H51007
Inparanoid	1	1.050	285	1.000	Inparanoid score	I2841
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D570949at33208
OrthoFinder	1	1.000	-	-		FOG0001650
OrthoInspector	1	1.000	-	-		oto40929
orthoMCL	1	0.900	-	-		OOG6_100940
Panther	1	1.100	-	-	LDO	PTHR12374
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R21
SonicParanoid	1	1.000	-	-		X4045
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790