Protein Alignment Ada2b and Tada2b

DIOPT Version :9

• Sequence 1: NP_001027151.1
• Gene: Ada2b / 40966
• FlyBaseID: FBgn0037555
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001163925.1
• Gene: Tada2b / 231151
• MGIID: 3035274
• Length: 420
• Species: Mus musculus
• Alignment Length: 570
• Identity: 172/570 - (30%)
• Similarity: 251/570 - (44%)
• Gaps: 173/570 - (30%)

  Fly     4 IADLFTKYNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVF 68
            :|:|..|| |..|..::..:|..|.||::.:||.:||:||||||.|:..|.||.:|.|...|...
Mouse     1 MAELGKKY-CVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGP 64

  Fly    69 RGKGAWTAREEIRLLDAIEQYGFGNWEDISKHI-ETKSAEDAKEEYVNKFVNGTIGRATWTPAQS 132
            ..:|.||:|||..|||||||:|||||||::.|: .:::.::..|.||:.:::|.:|:|.......
Mouse    65 EAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIP 129

  Fly   133 QRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNISLS 197
            .  |:.||| ....|||..:..:.||||:|:..|..||||||.||.:|.|||..||.|||.:|::
Mouse   130 N--RVTDHT-CPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVN 191

  Fly   198 SEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFF----RNRNYAQQQGLTKEQREFR 258
            .:|.:|::.||.||||:|.|:|:||.|||.:.|||.||..|.    :.:....::.:|||::|.|
Mouse   192 YDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKTLKRKITKEEKELR 256

  Fly   259 DRFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTG 323
            .:.|...||.:|.|::.|..::.:||.||.:..||.|||.||:||:.|...:|    .|.|:..
Mouse   257 LKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYE----AARHKRE- 316

  Fly   324 PYGHGKTDHTHTSNGSHRPPSSSLHSPQPNLRKVEMSSGGEASSNSIAPRNTLHIADPTCSGALL 388
                                           |:.|
Mouse   317 -------------------------------RRKE------------------------------ 320

  Fly   389 PSKNYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPTNSAKGSQQHLQPLQQH 453
             :||...|.||..                     .|..|....:.||
Mouse   321 -NKNLASSKRGKE---------------------DGKDSEFAAIENL------------------ 345

  Fly   454 PQLLQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLPQPPGSELLSHNELDLCKKHNITP 518
                                                        ||.||||..|..||...|::|
Mouse   346 --------------------------------------------PGFELLSDREKVLCSSLNLSP 366

  Fly   519 TTYLSVKTVCL-------SGAPS---LGSPMETSLRK----FFIKCGWLS 554
            ..|::|||:.:       .|.||   |.|.::..|:|    |..:.||:|
Mouse   367 ARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWIS 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	133/335 (40%)
		ZZ_ADA2	11..58	CDD:239075	21/46 (46%)
		SANT	73..115	CDD:238096	22/42 (52%)
Tada2b	NP_001163925.1	COG5114	6..415	CDD:227445	168/562 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849838
Domainoid	1	1.000	193	1.000	Domainoid score	I3206
eggNOG	1	0.900	-	-		E1_COG5114
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H51007
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2693
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001650
OrthoInspector	1	1.000	-	-		oto93293
orthoMCL	1	0.900	-	-		OOG6_100940
Panther	1	1.100	-	-	LDO	PTHR12374
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R21
SonicParanoid	1	1.000	-	-		X4045
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.780