Protein Alignment Ada2b and ada-2

DIOPT Version :10

• Sequence 1: NP_001027151.1
• Gene: Ada2b / 40966
• FlyBaseID: FBgn0037555
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001022133.1
• Gene: ada-2 / 174194
• WormBaseID: WBGene00017967
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 92/541 - (17%)
• Similarity: 148/541 - (27%)
• Gaps: 256/541 - (47%)

  Fly    11 YNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVFRGKGAWT 75
            :|||...|  |.|.|.|.||. ..:|:.||..|||...|:..|:|:.:...::..::     :||
 Worm    25 FNCTLRVD--QTIHVKCFECP-LRICILCFQCGAESPPHRRGHNYELVKPTSNPEAM-----SWT 81

  Fly    76 AREEIRLLDAIEQYGFGNWEDISKHI--ETKSAEDAKEEYVNKFVNGTIGR-----ATW------ 127
            ..:|..||.|..::..|||.:|::.|  ..|...:.|:.:...||.|.||:     ::|
 Worm    82 HEDEFELLKAAHKFKMGNWGEIAESIGRGRKDGHNCKDYFEKHFVRGWIGQFSIKSSSWDRIKYG 146

  Fly   128 --------------------------------------------------------------TPA 130
                                                                          ...
 Worm   147 MYINQTLDSVLQKNCLESTERMLLIRDAVRASGESWDENDPKLAIKVQQVLEQYVQKVIDGDIET 211

  Fly   131 QSQRPRLI----------------------------------DHTGDDDAGP------------- 148
            :.:||:.:                                  |...|:..||
 Worm   212 KYERPKFLTNQYETELSPDDCDPDNERDMKSKRSVKQEINTDDSDNDNSPGPSSSCRKKGPPSPK 276

  Fly   149 ----------------------------------------------------------------- 148
                                                                             
 Worm   277 RRKTTRVMRESSSDSDDDKSQASDKDTYHGMERETEEEDPPSAFETAQEFDTEDEEEEKKPKRGT 341

  Fly   149 ---------------------------------------------LGTNALSTLPPLEINSDEAM 168
                                                         .|.:...|.|.:. .|||..
 Worm   342 ASSSKRRKRRRMWVSKKDRRLHEFRKKMNQEVKELRSAYPRLLHESGVSKSETRPKMR-RSDELK 405

  Fly   169 QLGYMPNRDSFEREYDPTAEQLISNISLSSEDTEVDVML------KLAHVDIYTRRLRERARRKR 227
            .|||...|:..|.|:...||||||.:::|:.:.:.|..|      |.|.:..|.|.|..|..::.
 Worm   406 ILGYNNEREELECEWFNEAEQLISRLTISATEPQKDQRLDMENDIKFARLRHYVRLLGIRKAKRN 470

  Fly   228 MVRDYQLVS---NFFRNRNYA------QQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLERE 283
            .|.::..::   .|::...||      .||.:...:.|......:..||.|.:||..|..|:||.
 Worm   471 TVLEHDKINEFMKFYQEACYAAAKRPVSQQEIMDSRTEKEKLLAMTQQFLTRDEYRSLRASIERI 535

  Fly   284 KELRIRQSELYRYRYNGLTKI 304
            ..:..|...|...:.||.|.:
 Worm   536 DNVVERIEVLQDLQKNGETTL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada2b	NP_001027151.1	COG5114	10..>341	CDD:227445	92/541 (17%)
ada-2	NP_001022133.1	ZZ_ADA2	22..69	CDD:239075	19/46 (41%)
		COG5114	24..>126	CDD:227445	32/108 (30%)