DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNApol-iota and Esco2

DIOPT Version :9

Sequence 1:	NP_001287227.1	Gene:	DNApol-iota / 40965	FlyBaseID:	FBgn0037554	Length:	737	Species:	Drosophila melanogaster
Sequence 2:	NP_082315.3	Gene:	Esco2 / 71988	MGIID:	1919238	Length:	592	Species:	Mus musculus

Alignment Length:	247	Identity:	48/247 - (19%)
Similarity:	86/247 - (34%)	Gaps:	67/247 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 VQSITSLTNTSLTSPTAESPTSDEC--AFRSSPTTFKP---SDQFYRRRATTASPVPMLLDNGSE 493
            ||......:..|..|::...|::..  :|.:..:.|||   :..||.:.....:|:...|.....
Mouse    52 VQKEDKSCSHQLHFPSSPLKTTENSRFSFANHSSLFKPAMSTVSFYSKEKYYLNPLERKLIRECR 116

  Fly   494 SAATNSDFSDF---SETE-VEPSP---KKSRIGRLLVSKRSRLAADVGDSAAEVASPSKLRVCDL 551
            |....::..|.   |.|| ::..|   ||::      .|:..|.|....:...:.|.|:    :|
Mouse   117 SICLATESGDKPIPSVTENIQRKPVCTKKNK------KKQKSLTAKYQPNYKHIKSKSR----NL 171

  Fly   552 RLNSR----------DSEKD-FPMSTTPSTSTSAPAPRFRTVQPPNTLLQRI-------DGSLRF 598
            : ||:          |.|.. ||....|::             ||..|.|:|       .|:..|
Mouse   172 K-NSKPNQVTYKPVVDQENSCFPAKNYPNS-------------PPRVLSQKIKPQVTLQGGAAFF 222

  Fly   599 VTTRTASRLSSNASSTASSPLPSPMDDSIAMSAPSTTTLPFPSPTTTAVVTS 650
            |..|.:.:             ..|::|...:...:...:|..:|....:..|
Mouse   223 VRKRNSLK-------------KLPLEDKPLLLQKNLPEVPEGAPEAKQIPKS 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
DNApol-iota	NP_001287227.1	PolY_Pol_iota	18..411	CDD:176457
Esco2	NP_082315.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	267..294
		zf-C2H2_3	371..410	CDD:290589
		Acetyltransf_13	520..582	CDD:290591
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030