Protein Alignment PolI and poli

DIOPT Version :10

• Sequence 1: NP_649772.1
• Gene: PolI / 40965
• FlyBaseID: FBgn0037554
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001027479.2
• Gene: poli / 613070
• XenbaseID: XB-GENE-943046
• Length: 742
• Species: Xenopus tropicalis
• Alignment Length: 776
• Identity: 265/776 - (34%)
• Similarity: 374/776 - (48%)
• Gaps: 126/776 - (16%)

  Fly     7 LGKS-EAHQRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQKNIVVTCNYVARAKGVTKLMLIAE 70
            :|:| .:..|.|:|:|||.||||||.||:|.||:|.||||||.|||||||.||..||||||||.:
 Frog    41 VGRSGTSASRVIVHIDMDCFYAQVEMIRNPELRNKPLGIQQKYIVVTCNYEARKFGVTKLMLIKD 105

  Fly    71 AQRICPDLVLVNGEDLAPYRQMSQRIFDLLLNYTPLVEKLGFDENFMDVTALVELRQAHVAEALL 135
            |:..||.||||:||||.|||:||.|..:||..::|.||:||||||::|||.||:.:.........
 Frog   106 AREKCPQLVLVSGEDLTPYREMSYRATELLEEFSPQVERLGFDENYIDVTELVDKKLQEERGNGR 170

  Fly   136 RPPV-GHTYPADGTPLSNCDCGCAQRLAIGTRIAQEIREELKLRLGITCCAGIAYNKLLAKLVGS 199
            .|.| ||.|   .....|.:.....|:|.|:.||.|||..|..|||:|.|||.|.||||||||..
 Frog   171 NPGVCGHVY---SDQKMNVNDWAHVRIAAGSHIASEIRAALYNRLGLTGCAGTASNKLLAKLVSG 232

  Fly   200 SHEPNQQTVLVSTYAEQFMRELGDLKRVTGIGQKTQCLLLEAGMSSVEQLQQCDMDVMRKKFGFE 264
            :|:|||||.|:.......:..|..:||:.|||.||...|...|:|.:..||.|.:.::.|:||..
 Frog   233 THKPNQQTALLHESHSHLINSLDHVKRIPGIGYKTSKRLESLGLSRISDLQACPITLLEKEFGSS 297

  Fly   265 TATRLRDLAFGRDTSLVRPSGKPKTIGMEDA---CKPIS-VRTDVEERFRMLLKRLVEQVAEDGR 325
            .|.|::.|:.|.|.|.|.|||.|::|..||:   |..:| |:..:|||.|.||.|    :::|||
 Frog   298 VAHRIQMLSRGEDDSAVVPSGPPQSISDEDSFKKCSTVSEVKIKMEERLRNLLVR----ISKDGR 358

  Fly   326 VPIAIKVVLRKFDSQKKSSHRETKQANILPSLFKTSMCPGETGVSK-VQLADGAQDKLLKIVMRL 389
            :|..:::.:|:|....|..:||::|            ||....:|: :.....|...|::::|||
 Frog   359 IPHTLRLTIRQFSPSNKWFNRESRQ------------CPIPAHISQNIGAECQAVPALMELLMRL 411

  Fly   390 FERIVDMSKPFNITLLGLAFSKFQERKVGSSSIANFLIKKA--------------------DLEV 434
            ||:::|:...|::|||.:.||..:......|||..:|..||                    ...:
 Frog   412 FEKMIDVKMQFHLTLLNVCFSNLKASNSTRSSIGFYLTLKAPPAAATPLKGSTEAEQHTAESFPL 476

  Fly   435 QSITSLTNT---SLTSPTAESPTSDECAFRSSPTTFKPSDQFYRRRATTASPVPMLLDN----GS 492
            :..:|..:|   |:..|||..||:......:.|....|.         ..|.:|..:..    |.
 Frog   477 KENSSAPHTAPQSVGQPTAPVPTNHHTMLETLPEGIDPE---------VFSQLPEEIQQEIIAGQ 532

  Fly   493 ESAATNSDFSDFSETEVEPSPKKSRIGRLLVSKRSRLAADVGDSAAEVASPSKLRVCDLRLNSRD 557
            ..||.:|..|..|.::.:.:|.|   |.|....|:: |||:         ||:   ||..|....
 Frog   533 RHAAASSSSSVRSASKSQAAPPK---GILNFFSRAK-AADL---------PSQ---CDGVLLKEH 581

  Fly   558 SEKDFPMSTTPSTSTSAP---APRFRTVQPPNTLLQRIDGSL------------RFVTTRTASRL 607
            |:       |...||.||   :..|    |...:..|..|||            .:.|.::|.|.
 Frog   582 SQ-------TNRGSTEAPQGASSNF----PKGVVDVRPTGSLWDPKQEMHPFGQSYDTDQSAERC 635

  Fly   608 SSNASSTASSPLPSPMDDSIAMSAPSTTTLPFPSPTTTAVVTSSSSTATCDALTNIVCPAGVDAE 672
            .:.|         .|| ||...|:.|...||..|............       .....|..||..
 Frog   636 GTTA---------EPM-DSCCSSSTSCGQLPPQSAEMECAKAGGDQ-------ERAPFPHSVDVN 683

  Fly   673 VFKELPVELQTELIASWRSSLVAAVEQTNGTGAATSAAIASGAPATATTASGQKNTLYRYF 733
            ||.:||.|:|.||:|.|:.     ::.|........:..|..:....|.||...::|.:||
 Frog   684 VFSQLPEEVQRELMAEWKQ-----LKPTPKIPVRKQSEKAKASRGKRTGASAGASSLLKYF 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PolI	NP_649772.1	PolY_Pol_iota	18..411	CDD:176457	177/398 (44%)
poli	NP_001027479.2	PolY	53..433	CDD:452909	177/398 (44%)
		UBM	509..533	CDD:464159	5/32 (16%)