Protein Alignment PolI and Poli

DIOPT Version :10

• Sequence 1: NP_649772.1
• Gene: PolI / 40965
• FlyBaseID: FBgn0037554
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_063133258.1
• Gene: Poli / 291526
• RGDID: 1305212
• Length: 788
• Species: Rattus norvegicus
• Alignment Length: 796
• Identity: 249/796 - (31%)
• Similarity: 368/796 - (46%)
• Gaps: 165/796 - (20%)

  Fly    12 AHQRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQKNIVVTCNYVARAKGVTKLMLIAEAQRICP 76
            |..|.|:|:|:|.||||||.|.:|.|:.|.||:|||.:||||||.||..||.|||.:.:|:..||
  Rat    45 ASSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCP 109

  Fly    77 DLVLVNGEDLAPYRQMSQRIFDLLLNYTPLVEKLGFDENFMDVTALVE--LRQAHVAEALLRPPV 139
            .|||||||||:.||:||.::.:||..::|.||:|||||||:|:|.:||  |:|....|.   |.|
  Rat   110 QLVLVNGEDLSRYREMSYKVTELLEEFSPAVERLGFDENFVDLTEMVEKRLQQLPSDEV---PSV 171

  Fly   140 ---GHTYPADGTPLSNCDCGCAQRLAIGTRIAQEIREELKLRLGITCCAGIAYNKLLAKLVGSSH 201
               ||.|.....   |.......|||:|::||.|:||.:..:||:|.|||:|.||||||||....
  Rat   172 TMSGHVYNNQSV---NLHSSTHVRLAVGSQIAAEMREAMHNQLGLTGCAGVAPNKLLAKLVSGVF 233

  Fly   202 EPNQQTVLVSTYAEQFMRELGDLKRVTGIGQKTQCLLLEAGMSSVEQLQQCDMDVMRKKFGFETA 266
            :|||||||:....:..:..|..:|.:.|||.||...|...|::||..||...:..:.|:.|...|
  Rat   234 KPNQQTVLLPESCQHLIHSLNHIKEMPGIGYKTAKRLEVLGINSVHDLQTFPIKTLEKELGISVA 298

  Fly   267 TRLRDLAFGRDTSLVRPSGKPKTIGMEDACKPISVRTDVEERFRMLLKRLVEQVAEDGRVPIAIK 331
            .|:|.|:||.|.|.|.|||.|::...||..|..|...:.:.:...||..|:.:|..|||.|..|:
  Rat   299 QRIRKLSFGEDKSPVTPSGPPQSFSEEDTFKKCSSEVEAKTKIEELLSSLLNRVCHDGRKPHTIR 363

  Fly   332 VVLRKFDSQKKSSHRETKQANILPSLFKTSMCPGETGVSKVQLADGAQD---KLLKIVMRLFERI 393
            :|:|::..  |..:||::|            ||..:.|.: :|..|..|   .|::|:|:||..:
  Rat   364 LVIRRYSD--KHCNRESRQ------------CPIPSHVIQ-KLGTGNYDAVPPLMEILMKLFRNM 413

  Fly   394 VDMSKPFNITLLGLAFSKFQERKVGSSSIANFLIKKADLEVQSITSLTNTSLTSPTA-------- 450
            |::...|::|||.:.|...   |..:|:      ||..::....:||:.|:.:...:
  Rat   414 VNVKMAFHLTLLSVCFCNL---KALNSA------KKGPMDCFLTSSLSTTACSGKRSFKVKDIHM 469

  Fly   451 -----ESPTSDEC----AFRSSPTTFKPSDQ--FYRRRATTASPVPMLLD--------------- 489
                 |...:.:|    ...|:.....|||.  |.:.:.|:..|:..|.:
  Rat   470 EDSYKEKEANWDCLPSRRIESTRRGESPSDATCFPKEKDTSDLPLQFLPEGVDQEVFTQLPADIQ 534

  Fly   490 --------------NGSESA---ATNSDFSDFSETEVEP---SPKKSRIGRLLVSKRSRLAA--D 532
                          .||.|.   |:....|.||..:.:.   ||:.:    ||..|::...:  :
  Rat   535 EEILSGKSRENLQGKGSLSCPLHASRGVLSFFSTKQTQAGCLSPRDT----LLTGKQASAVSPCE 595

  Fly   533 VGDSAAEVAS---PSKLRVCDLRLNSRDSEKDFPMSTTPSTSTSAPAPRFRTVQP--------PN 586
            .|.|....:|   ||..:.|...::::  .||..||..|   |.:....|....|        ||
  Rat   596 PGTSGLSTSSSSHPSCGKDCSYYVDNQ--LKDERMSQGP---TESQGFHFSNTNPAVSVFHSFPN 655

  Fly   587 TLLQRIDGSLRFVTTRTASRLSSNASSTASSPLPSPMDDSIAMSAPSTTTLPFPSPTTTAVVTSS 651
            ...:::     |.|.|||......| :|:...|.:...||      :...|.|||
  Rat   656 LQSEQL-----FSTHRTADSHKQTA-TTSHQGLENREQDS------ADEKLTFPS---------- 698

  Fly   652 SSTATCDALTNIVCPAGVDAEVFKELPVELQTELIASWRSSLVAAVEQTNGTGAATSAAIAS--G 714
                            .:|.:||.|||.|:|.||:|.|:.:           ||...:...|  |
  Rat   699 ----------------DIDPQVFYELPEEVQRELMAEWKRA-----------GAEFPSVHNSVCG 736

  Fly   715 APATATTASGQKNTLY 730
            .||........:..||
  Rat   737 VPAGLELTIAAEEDLY 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PolI	NP_649772.1	PolY_Pol_iota	18..411	CDD:176457	167/400 (42%)
Poli	XP_063133258.1	None